Detailed information of TA system TA097778

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 35870..36405
• Replicon: plasmid pPAR01
• Accession: NZ_CP027261
• Organism: Pectobacterium parmentieri strain IFB5427

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C5E18_RS24295
• Protein ID: WP_127088017.1
• Coordinates: 36118..36405 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C5E18_RS24290
• Protein ID: WP_127088016.1
• Coordinates: 35870..36121 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E18_RS24275	31878..33074	+	1197	WP_127088013.1	conjugal transfer protein TraW	-
C5E18_RS24280	33071..33583	+	513	WP_127088014.1	conjugal transfer protein TraX	-
C5E18_RS24285	33637..35781	+	2145	WP_127088015.1	DotA/TraY family protein	-
C5E18_RS24290	35870..36121	+	252	WP_127088016.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C5E18_RS24295	36118..36405	+	288	WP_127088017.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C5E18_RS24300	36423..37103	+	681	WP_127088018.1	plasmid IncI1-type surface exclusion protein ExcA	-
C5E18_RS24305	37199..38464	+	1266	WP_127088019.1	conjugal transfer protein TrbA	-
C5E18_RS24310	38469..39518	+	1050	WP_127088020.1	DsbC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..101998	101998

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-85)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11069.02 Da
• Isoelectric Point: 10.6797

>T97778 WP_127088017.1 NZ_CP027261:36118-36405 [Pectobacterium parmentieri]
MTYKIKFRTDALKEWNHLDKSIQQQFAKKLKVCAENPHIPSAKLRGMPDCYNIKLRASGFRLVYQVINNELIIAVVAVGK
REHNQVYNLASKRLR

Nucleotide

• Length: 288 bp

>T97778 NZ_CP027261:36118-36405 [Pectobacterium parmentieri]
ATGACCTATAAGATTAAGTTCAGGACTGACGCGCTCAAAGAGTGGAATCATCTTGATAAATCTATTCAGCAACAATTTGC
CAAAAAACTAAAGGTTTGTGCGGAAAACCCGCACATACCTTCTGCAAAACTGAGAGGGATGCCTGACTGCTACAACATAA
AATTACGTGCTTCAGGCTTCCGACTTGTTTATCAGGTTATTAACAATGAATTAATCATTGCTGTCGTTGCAGTTGGAAAA
CGGGAGCATAATCAAGTTTACAATCTGGCCAGCAAACGGCTCAGATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9340.59 Da
• Isoelectric Point: 4.5297

>AT97778 WP_127088016.1 NZ_CP027261:35870-36121 [Pectobacterium parmentieri]
MPNTIHSDTTASVSELKKNPMATVKAGAGYPVAIMNHNQPAFYCVPAELYEQMLEYIDDQELAALVEKRSKQTLHDVELE
QYL

Nucleotide

• Length: 252 bp

>AT97778 NZ_CP027261:35870-36121 [Pectobacterium parmentieri]
ATGCCAAATACTATTCATAGCGACACAACCGCAAGTGTCAGCGAGCTGAAGAAAAACCCCATGGCCACAGTCAAAGCTGG
GGCGGGTTATCCGGTGGCAATAATGAACCACAACCAACCTGCTTTCTACTGTGTTCCTGCTGAACTCTATGAACAGATGC
TGGAATATATCGACGATCAGGAACTCGCGGCGCTGGTTGAAAAGCGGAGCAAGCAAACCCTGCATGACGTTGAGCTGGAA
CAGTATCTATGA