Detailed information of TA system TA097729

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3464090..3464731
• Replicon: chromosome
• Accession: NZ_CP027246
• Organism: Acinetobacter baumannii strain WCHAB005078

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: B0V6V2
• Locus tag: C6N18_RS17700
• Protein ID: WP_000931890.1
• Coordinates: 3464090..3464479 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: C6N18_RS17705
• Protein ID: WP_011860336.1
• Coordinates: 3464486..3464731 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6N18_RS17685	3459208..3461403	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
C6N18_RS17690	3461591..3462157	-	567	WP_000651536.1	rhombosortase	-
C6N18_RS17695	3462235..3463320	-	1086	WP_000049106.1	hypothetical protein	-
C6N18_RS17700	3464090..3464479	-	390	WP_000931890.1	membrane protein	Toxin
C6N18_RS17705	3464486..3464731	-	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
C6N18_RS17710	3464931..3466103	+	1173	WP_001190546.1	acyl-CoA dehydrogenase family protein	-
C6N18_RS17715	3466153..3467643	-	1491	WP_000415133.1	NAD(P)/FAD-dependent oxidoreductase	-
C6N18_RS17720	3467824..3468201	-	378	WP_001216380.1	50S ribosomal protein L17	-
C6N18_RS17725	3468220..3469227	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15649.98 Da
• Isoelectric Point: 10.4623

>T97729 WP_000931890.1 NZ_CP027246:c3464479-3464090 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T97729 NZ_CP027246:c3464479-3464090 [Acinetobacter baumannii]
TTGCTCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATAAGCTTTATTTTCTTTT
TAAAGCGTCCGCAACTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT97729 WP_011860336.1 NZ_CP027246:c3464731-3464486 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT97729 NZ_CP027246:c3464731-3464486 [Acinetobacter baumannii]
ATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTTTGACCCTTATGT
GAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAGATCCTGATTTAC
TCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAACACTATGTTCAT
GGTTAA

Structures

Toxin

• AlphaFold DB: A0A0J1A4U0