Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 2909982..2910550 Replicon chromosome
Accession NZ_CP027236
Organism Actinomyces sp. oral taxon 897 strain F0631

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag C3V41_RS11475 Protein ID WP_106110363.1
Coordinates 2909982..2910323 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag C3V41_RS11480 Protein ID WP_106110364.1
Coordinates 2910317..2910550 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3V41_RS11455 2905336..2907702 + 2367 WP_106110359.1 phosphoribosylformylglycinamidine synthase subunit PurL -
C3V41_RS11460 2907807..2908148 + 342 WP_174714815.1 nuclear transport factor 2 family protein -
C3V41_RS11465 2908287..2908640 - 354 WP_106110361.1 MerR family transcriptional regulator -
C3V41_RS11470 2908777..2909898 + 1122 WP_106110362.1 MFS transporter -
C3V41_RS11475 2909982..2910323 - 342 WP_106110363.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
C3V41_RS11480 2910317..2910550 - 234 WP_106110364.1 ribbon-helix-helix domain-containing protein Antitoxin
C3V41_RS11490 2914050..2915039 + 990 WP_106110365.1 DUF3152 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12156.90 Da        Isoelectric Point: 4.7914

>T97722 WP_106110363.1 NZ_CP027236:c2910323-2909982 [Actinomyces sp. oral taxon 897]
VVARGEIWWADFSEPVGSEPEYLRPALIISSDRFNQSHISTVIVSAITSNMRLAAAPGNVELERGEGGVPKDCVVNVSQT
LVVDRSRLVDPVGTLPAHLLARVDDGLRLVLGL

Download         Length: 342 bp

>T97722 NZ_CP027236:c2910323-2909982 [Actinomyces sp. oral taxon 897]
GTGGTAGCCCGGGGCGAGATCTGGTGGGCCGACTTCAGCGAGCCGGTGGGCTCAGAACCCGAATACCTACGTCCAGCCCT
CATTATCTCCTCCGACCGCTTTAACCAGTCACACATTTCCACGGTTATCGTTTCTGCGATCACCAGCAACATGCGCCTGG
CCGCGGCACCGGGCAATGTCGAACTCGAGCGGGGAGAAGGAGGTGTGCCGAAGGACTGCGTCGTGAACGTGTCGCAGACG
CTCGTCGTGGACCGTTCCAGGCTGGTCGACCCCGTTGGCACCCTGCCCGCCCACCTCCTGGCACGGGTCGATGACGGGCT
GCGGCTGGTCCTGGGGCTCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8383.45 Da        Isoelectric Point: 4.9681

>AT97722 WP_106110364.1 NZ_CP027236:c2910550-2910317 [Actinomyces sp. oral taxon 897]
VKTAISVPDPLFHKAEQLARRLGWSRSQLYAQAVRELIARQGDDPVTAALNDLADEMGAETPPSAGRALIQAGAWEW

Download         Length: 234 bp

>AT97722 NZ_CP027236:c2910550-2910317 [Actinomyces sp. oral taxon 897]
GTGAAGACCGCGATCTCCGTTCCCGACCCGCTTTTCCACAAGGCTGAACAGCTCGCACGCCGCCTGGGGTGGAGCAGGTC
GCAGCTCTACGCTCAAGCGGTCCGTGAGCTCATTGCCCGTCAGGGTGACGACCCGGTGACCGCTGCGCTCAATGACCTGG
CAGACGAGATGGGCGCCGAGACACCGCCCTCGGCCGGGCGCGCGCTCATCCAGGCAGGAGCGTGGGAGTGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References