Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 271956..272478 Replicon chromosome
Accession NZ_CP027236
Organism Actinomyces sp. oral taxon 897 strain F0631

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C3V41_RS01150 Protein ID WP_106108741.1
Coordinates 272215..272478 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C3V41_RS01145 Protein ID WP_106108740.1
Coordinates 271956..272213 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3V41_RS13270 267715..268923 + 1209 WP_174714736.1 hypothetical protein -
C3V41_RS01130 269156..269368 + 213 WP_106108738.1 50S ribosomal protein L31 -
C3V41_RS01135 269495..270586 + 1092 WP_106108739.1 peptide chain release factor 1 -
C3V41_RS01140 270888..271730 + 843 WP_106110580.1 peptide chain release factor N(5)-glutamine methyltransferase -
C3V41_RS01145 271956..272213 + 258 WP_106108740.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C3V41_RS01150 272215..272478 + 264 WP_106108741.1 Txe/YoeB family addiction module toxin Toxin
C3V41_RS01155 272552..273265 + 714 WP_106108742.1 DNA alkylation repair protein -
C3V41_RS12995 273505..273663 + 159 WP_165271558.1 hypothetical protein -
C3V41_RS01160 273667..275916 + 2250 WP_106108743.1 DEAD/DEAH box helicase -
C3V41_RS01165 276135..276485 + 351 WP_106108744.1 helix-turn-helix domain-containing protein -
C3V41_RS01170 276485..277333 + 849 WP_106108745.1 ImmA/IrrE family metallo-endopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10607.95 Da        Isoelectric Point: 7.5572

>T97720 WP_106108741.1 NZ_CP027236:272215-272478 [Actinomyces sp. oral taxon 897]
MTLIWSDQAWEDYLWWQLHDRKVRRRINLLLHDIQRSGHEGIGKPEPLRYQLTGHWSRRITDEHRLVYRIDDGGDIHIVA
CRHHYGD

Download         Length: 264 bp

>T97720 NZ_CP027236:272215-272478 [Actinomyces sp. oral taxon 897]
ATGACGCTCATCTGGTCCGATCAGGCCTGGGAGGACTACCTGTGGTGGCAGCTCCATGACCGCAAGGTGCGCAGGCGCAT
TAACCTGCTCCTGCACGACATCCAGCGCTCCGGCCACGAGGGGATTGGCAAGCCCGAGCCTTTGCGGTACCAGCTGACCG
GCCACTGGTCACGGCGCATTACCGACGAGCACCGCCTCGTCTACCGCATCGATGACGGTGGGGACATCCACATCGTGGCC
TGCCGCCACCACTACGGCGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9379.58 Da        Isoelectric Point: 4.4887

>AT97720 WP_106108740.1 NZ_CP027236:271956-272213 [Actinomyces sp. oral taxon 897]
VKIMSYTESRAHYAEVLDSVIDDCEEVVITRAGHAPAVIVSLAEYQSLKETDYLLRNPANAKRLLESIASLEAGHGTVHE
LIELD

Download         Length: 258 bp

>AT97720 NZ_CP027236:271956-272213 [Actinomyces sp. oral taxon 897]
GTGAAGATCATGAGCTACACCGAGTCCCGCGCCCACTACGCCGAGGTACTGGACTCCGTCATTGACGACTGCGAGGAGGT
CGTCATCACCCGGGCCGGGCACGCTCCGGCGGTCATTGTCTCGCTGGCGGAGTACCAGTCCCTCAAGGAGACCGACTACC
TCCTGCGCAACCCCGCCAATGCCAAGCGCCTGCTGGAGTCGATCGCCTCATTGGAGGCTGGCCACGGCACCGTCCACGAG
CTCATCGAGCTGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References