Detailed information of TA system TA097719

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 1039448..1040019
• Replicon: chromosome
• Accession: NZ_CP027235
• Organism: Haemophilus sp. oral taxon 036 strain F0629

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C3V42_RS04985
• Protein ID: WP_106013873.1
• Coordinates: 1039729..1040019 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C3V42_RS04980
• Protein ID: WP_106014311.1
• Coordinates: 1039448..1039729 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3V42_RS04970	1037018..1038604	+	1587	WP_106013872.1	DNA recombination protein RmuC	-
C3V42_RS04975	1038751..1039302	+	552	WP_065264898.1	TIGR00645 family protein	-
C3V42_RS04980	1039448..1039729	+	282	WP_106014311.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
C3V42_RS04985	1039729..1040019	+	291	WP_106013873.1	type II toxin-antitoxin system YafQ family toxin	Toxin
C3V42_RS04990	1040223..1041425	-	1203	WP_106013874.1	aromatic amino acid transporter	-
C3V42_RS04995	1041611..1042474	+	864	WP_106013875.1	YicC family protein	-
C3V42_RS05000	1042484..1043323	+	840	WP_106013876.1	folate-binding protein YgfZ	-
C3V42_RS05005	1043375..1043857	-	483	WP_106013877.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
C3V42_RS05010	1043868..1044449	-	582	WP_046943119.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (10-96)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11307.17 Da
• Isoelectric Point: 8.8885

>T97719 WP_106013873.1 NZ_CP027235:1039729-1040019 [Haemophilus sp. oral taxon 036]
MGMESVKTLKVTATKTFQRDVKKLTAKQQFSVEMTEVLYLLQRNRTLPKKYLDHSLQGEMQGYRDCHIFNDLVLIYQIID
NEELKLIRIGSHSEIF

Nucleotide

• Length: 291 bp

>T97719 NZ_CP027235:1039729-1040019 [Haemophilus sp. oral taxon 036]
ATGGGTATGGAATCAGTTAAAACATTAAAAGTAACTGCAACTAAAACATTTCAACGAGATGTTAAAAAGCTCACAGCTAA
GCAACAATTTTCAGTAGAGATGACTGAGGTTTTGTATCTTTTACAAAGAAATCGAACGCTTCCAAAAAAATACTTAGATC
ACTCACTACAAGGTGAAATGCAAGGTTATCGTGACTGCCATATTTTTAACGATCTTGTGCTGATTTACCAAATTATTGAT
AACGAAGAATTAAAGCTTATTCGTATTGGTTCACATTCAGAAATTTTCTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10531.87 Da
• Isoelectric Point: 4.2837

>AT97719 WP_106014311.1 NZ_CP027235:1039448-1039729 [Haemophilus sp. oral taxon 036]
MTQNASFSFRLSENLKHEAFNVIENYGFTPSQVFNLFLTEIANTKTIPVNLSYLKPNAETLRAMQEAENGDIDIISEANF
EADIMENLLKSVK

Nucleotide

• Length: 282 bp

>AT97719 NZ_CP027235:1039448-1039729 [Haemophilus sp. oral taxon 036]
ATGACACAAAATGCATCTTTTAGCTTTCGTTTATCAGAAAATTTAAAACATGAGGCTTTTAATGTAATTGAAAATTACGG
TTTCACCCCTTCGCAAGTGTTTAATTTATTTTTAACAGAAATTGCGAATACAAAAACGATTCCAGTAAACCTTTCTTATT
TGAAACCAAATGCTGAAACATTACGTGCTATGCAAGAAGCTGAAAATGGTGATATTGATATCATTAGTGAAGCAAATTTT
GAAGCCGACATTATGGAAAATCTATTAAAATCAGTGAAATAA