Detailed information of TA system TA097718

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeUV (cbtA-cbeA)/CbtA-CbeA
• Location: 4963398..4964181
• Replicon: chromosome
• Accession: NZ_CP027225
• Organism: Phytobacter sp. SCO41

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: C5523_RS24145
• Protein ID: WP_172960934.1
• Coordinates: 4963398..4963766 (-)
• Length: 123 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: C5523_RS24150
• Protein ID: WP_108702120.1
• Coordinates: 4963822..4964181 (-)
• Length: 120 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5523_RS24120	4958713..4958994	-	282	WP_108702115.1	hypothetical protein	-
C5523_RS24125	4959233..4960099	+	867	WP_108702116.1	hypothetical protein	-
C5523_RS24130	4960476..4961264	-	789	WP_108702117.1	helix-turn-helix domain-containing protein	-
C5523_RS24135	4961870..4962859	+	990	WP_108702118.1	glycosyltransferase	-
C5523_RS24140	4962998..4963318	+	321	WP_088912244.1	hypothetical protein	-
C5523_RS24145	4963398..4963766	-	369	WP_172960934.1	TA system toxin CbtA family protein	Toxin
C5523_RS24150	4963822..4964181	-	360	WP_108702120.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5523_RS24155	4964204..4964425	-	222	WP_108702121.1	DUF987 domain-containing protein	-
C5523_RS24160	4964439..4964921	-	483	WP_108702122.1	DNA repair protein RadC	-
C5523_RS24165	4964918..4965151	-	234	WP_064167588.1	hypothetical protein	-
C5523_RS24170	4965162..4965641	-	480	WP_108702123.1	antirestriction protein	-
C5523_RS24175	4965712..4966533	-	822	WP_108702124.1	DUF945 domain-containing protein	-
C5523_RS24180	4966644..4966856	-	213	WP_108702125.1	hypothetical protein	-
C5523_RS24185	4966938..4967297	-	360	WP_108702126.1	hypothetical protein	-
C5523_RS24190	4967353..4967763	-	411	WP_108702377.1	hypothetical protein	-
C5523_RS24195	4967871..4968548	-	678	WP_038418587.1	WYL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4947978..4986286	38308

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (7-110)

Antitoxin

• Antitoxin CbeA (16-114)

Sequences

Toxin

Protein

• Length: 123 a.a.
• Molecular weight: 13516.30 Da
• Isoelectric Point: 7.2755

>T97718 WP_172960934.1 NZ_CP027225:c4963766-4963398 [Phytobacter sp. SCO41]
IQSMPPQRAASSRLSSVEIWQKLLEYLPEQHYGLTLNDTPFGNDSVIQKHIDAGISLCDAVNFIVEKYDLVRTDRHGFSV
KEQSPFIGSIDMLRARKATGLMTLNGYQTVTDITSGRSSGGK

Nucleotide

• Length: 369 bp

>T97718 NZ_CP027225:c4963766-4963398 [Phytobacter sp. SCO41]
ATACAATCCATGCCCCCTCAAAGGGCGGCATCGTCACGTCTGTCATCAGTCGAAATCTGGCAAAAATTACTGGAGTATCT
GCCGGAGCAACACTACGGCCTTACCCTCAACGACACACCGTTTGGCAACGACAGTGTGATCCAGAAACACATTGATGCGG
GAATCTCACTGTGTGACGCGGTGAATTTTATCGTGGAAAAGTACGACCTGGTGCGTACTGACCGTCACGGCTTCAGCGTG
AAAGAGCAGTCTCCGTTTATCGGCAGCATCGATATGCTCCGCGCCCGGAAGGCTACCGGGCTGATGACACTCAATGGCTA
TCAAACCGTTACTGACATCACCAGTGGTAGATCCAGCGGAGGGAAATAA

Antitoxin

Protein

• Length: 120 a.a.
• Molecular weight: 13355.39 Da
• Isoelectric Point: 7.3727

>AT97718 WP_108702120.1 NZ_CP027225:c4964181-4963822 [Phytobacter sp. SCO41]
MQKATRVINHNIAESWWGLRRNITPCFGARLVQEGNHLHYLADRASIAGTFNDADLRHLDQAFPVLMKQMELMLTSNELT
PHIQRCITLHAKGLICEADTLGSCGYLYIVIYPTSATTA

Nucleotide

• Length: 360 bp

>AT97718 NZ_CP027225:c4964181-4963822 [Phytobacter sp. SCO41]
ATGCAGAAAGCAACCCGTGTAATCAACCATAACATCGCGGAATCCTGGTGGGGCCTCAGACGCAACATCACGCCGTGTTT
TGGTGCCCGGCTGGTACAGGAGGGTAACCACCTGCATTACCTTGCTGACCGTGCCAGCATTGCCGGGACATTTAATGACG
CAGATTTACGCCATCTGGACCAGGCATTTCCGGTACTGATGAAGCAGATGGAGCTTATGCTGACCAGCAACGAACTCACG
CCCCACATTCAGCGCTGCATCACGCTCCACGCAAAAGGGCTGATATGTGAGGCCGATACGCTCGGCTCCTGTGGCTATCT
GTACATCGTAATTTATCCGACATCTGCAACAACCGCATAA