Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2002542..2003132 Replicon chromosome
Accession NZ_CP027225
Organism Phytobacter sp. SCO41

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag C5523_RS09630 Protein ID WP_107224096.1
Coordinates 2002800..2003132 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag C5523_RS09625 Protein ID WP_108701019.1
Coordinates 2002542..2002799 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5523_RS09595 1998147..1998482 - 336 WP_041851877.1 gamma-glutamylcyclotransferase -
C5523_RS09600 1998609..1998899 - 291 WP_041851876.1 DUF3601 domain-containing protein -
C5523_RS09605 1999157..1999696 - 540 WP_079496546.1 ester cyclase -
C5523_RS09615 1999996..2001105 - 1110 WP_108701017.1 alkene reductase -
C5523_RS09620 2001206..2002117 + 912 WP_108701018.1 LysR family transcriptional regulator -
C5523_RS09625 2002542..2002799 + 258 WP_108701019.1 antitoxin Antitoxin
C5523_RS09630 2002800..2003132 + 333 WP_107224096.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
C5523_RS09640 2003533..2004966 + 1434 WP_107224097.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
C5523_RS09650 2005220..2006131 - 912 WP_071196350.1 sugar ABC transporter permease -
C5523_RS09655 2006150..2007424 - 1275 WP_071196351.1 extracellular solute-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11709.43 Da        Isoelectric Point: 8.0290

>T97706 WP_107224096.1 NZ_CP027225:2002800-2003132 [Phytobacter sp. SCO41]
MDRGEIWLVSLDPTTGHEQSGKRPVLIVSPASFNALTRLPVVVPVTSGGNFARAAGFAVSLDGAGTKTTGVIRCDQPRTI
DMDARNGKRLERIPDAVVNEVLARLEAILS

Download         Length: 333 bp

>T97706 NZ_CP027225:2002800-2003132 [Phytobacter sp. SCO41]
ATGGACAGAGGGGAAATCTGGCTCGTTTCACTGGATCCGACCACCGGGCATGAACAAAGCGGAAAACGTCCAGTGCTTAT
CGTTTCTCCCGCGTCATTTAATGCACTCACCCGTTTGCCCGTTGTTGTTCCGGTCACCAGTGGCGGAAACTTTGCCCGAG
CGGCGGGTTTTGCCGTCTCACTGGACGGTGCGGGAACGAAAACCACGGGTGTGATTCGCTGCGATCAGCCCAGAACCATT
GATATGGACGCCCGAAATGGCAAGCGTCTGGAACGTATACCCGATGCTGTCGTGAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGTTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9316.79 Da        Isoelectric Point: 4.5799

>AT97706 WP_108701019.1 NZ_CP027225:2002542-2002799 [Phytobacter sp. SCO41]
MYIARLKKVGGSVMLAVPPTVLKTLGLSTDSEVGMTIENGCLIIEPQKRPHYSLEELLAQCDPHAEISEEDRQWIDAPAA
GKELL

Download         Length: 258 bp

>AT97706 NZ_CP027225:2002542-2002799 [Phytobacter sp. SCO41]
ATGTATATCGCTCGCCTTAAAAAGGTTGGAGGATCCGTCATGCTGGCGGTTCCTCCTACCGTATTGAAAACCCTGGGGCT
GTCGACGGATAGCGAAGTGGGTATGACCATTGAGAATGGTTGCCTGATTATTGAACCCCAGAAACGGCCACATTACTCGC
TTGAGGAATTGCTGGCGCAGTGTGATCCGCACGCCGAAATCAGCGAAGAGGATCGGCAATGGATTGATGCGCCTGCGGCG
GGCAAGGAGCTTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References