Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 942579..943242 Replicon chromosome
Accession NZ_CP027225
Organism Phytobacter sp. SCO41

Toxin (Protein)


Gene name cptA Uniprot ID A0A348D8P9
Locus tag C5523_RS04665 Protein ID WP_039077972.1
Coordinates 942826..943242 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A348D8P8
Locus tag C5523_RS04660 Protein ID WP_039077973.1
Coordinates 942579..942845 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5523_RS04635 937757..939190 - 1434 WP_108700659.1 6-phospho-beta-glucosidase -
C5523_RS04640 939313..940041 - 729 WP_039077977.1 MurR/RpiR family transcriptional regulator -
C5523_RS04645 940094..940405 + 312 WP_108700660.1 N(4)-acetylcytidine aminohydrolase -
C5523_RS04650 940568..941227 + 660 WP_039077975.1 hemolysin III family protein -
C5523_RS04655 941346..942329 - 984 WP_071196007.1 tRNA-modifying protein YgfZ -
C5523_RS04660 942579..942845 + 267 WP_039077973.1 FAD assembly factor SdhE Antitoxin
C5523_RS04665 942826..943242 + 417 WP_039077972.1 protein YgfX Toxin
C5523_RS04670 943245..943766 - 522 WP_039077971.1 flavodoxin FldB -
C5523_RS04675 943868..944764 + 897 WP_039077970.1 site-specific tyrosine recombinase XerD -
C5523_RS04680 944789..945502 + 714 WP_039077969.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
C5523_RS04685 945508..947241 + 1734 WP_039077968.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16438.33 Da        Isoelectric Point: 11.4778

>T97705 WP_039077972.1 NZ_CP027225:942826-943242 [Phytobacter sp. SCO41]
VVLWQSDIRVSWRSQWLSLLLHGLMAAFVLLLPWPLSYTPLWLLLLSLVVFDSVRSQRRINACQGEIKLLMDARLRWQGV
EWEIVGTPWMLNIGMILRLRREKDGRRQHLWLAADSMDAQEWRDLRRLISQQSAQRQH

Download         Length: 417 bp

>T97705 NZ_CP027225:942826-943242 [Phytobacter sp. SCO41]
GTGGTCCTGTGGCAATCTGATATACGCGTCTCATGGCGCTCACAGTGGCTCTCACTTTTACTCCATGGCTTGATGGCGGC
TTTCGTGTTGCTGTTACCCTGGCCATTGAGCTATACGCCGCTTTGGTTACTGCTTTTGTCACTGGTGGTGTTCGACAGCG
TACGGAGTCAGCGCCGCATTAATGCCTGTCAGGGAGAGATCAAACTGCTGATGGATGCACGTTTGCGCTGGCAAGGCGTG
GAGTGGGAAATCGTAGGAACACCGTGGATGCTGAATATTGGCATGATTCTGCGTTTGCGTCGGGAAAAAGATGGTCGCCG
ACAGCATCTGTGGCTGGCCGCAGATAGCATGGATGCGCAAGAGTGGCGTGATTTGCGCCGACTGATTTCGCAACAATCGG
CGCAGCGTCAGCACTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.03 Da        Isoelectric Point: 6.2199

>AT97705 WP_039077973.1 NZ_CP027225:942579-942845 [Phytobacter sp. SCO41]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRVFVRLLQSDDPDLFNWLMNHGKPQDEALQRMIQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT97705 NZ_CP027225:942579-942845 [Phytobacter sp. SCO41]
ATGGATATTAACAACAAAGCCCGTATTCATTGGGCATGTCGGCGCGGAATGCGTGAGCTGGATATTTCCATCATGCCTTT
CTTTGAACATGAATATGATTCGCTGAGTGATGATGACAAACGTGTGTTTGTGCGTCTTCTGCAGAGCGATGACCCTGATT
TATTTAACTGGCTGATGAATCACGGCAAACCTCAGGACGAGGCGTTGCAGCGAATGATCCAGTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348D8P9

Antitoxin

Source ID Structure
AlphaFold DB A0A348D8P8

References