Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1992714..1992985 Replicon chromosome
Accession NZ_CP027219
Organism Escherichia coli strain 2015C-3163

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1992844..1992947 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1992714..1992985 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H73_RS10775 1989269..1989931 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6H73_RS10780 1989955..1990611 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6H73_RS10785 1990713..1990943 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6H73_RS10790 1991082..1991456 + 375 WP_000204700.1 CopC domain-containing protein YobA -
C6H73_RS10795 1991460..1992332 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6H73_RS10800 1992345..1992686 + 342 WP_000976472.1 YebY family protein -
- 1992714..1992985 - 272 - - Antitoxin
- 1992844..1992947 + 104 - - Toxin
C6H73_RS10805 1993082..1993738 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
C6H73_RS10810 1993739..1993930 - 192 WP_001296140.1 YebW family protein -
C6H73_RS10815 1994035..1994271 - 237 WP_001295499.1 DUF1480 family protein -
C6H73_RS10820 1994389..1995828 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T97649 NZ_CP027219:1992844-1992947 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT97649 NZ_CP027219:c1992985-1992714 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACATATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References