Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3064004..3065251 Replicon chromosome
Accession NZ_CP027218
Organism Pseudomonas sp. DTU12.3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C2E19_RS14060 Protein ID WP_129393223.1
Coordinates 3064004..3064618 (-) Length 205 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C2E19_RS14065 Protein ID WP_129393226.1
Coordinates 3064694..3065251 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2E19_RS14035 3060357..3061124 - 768 WP_129393210.1 phosphonate ABC transporter, permease protein PhnE -
C2E19_RS14040 3061121..3061948 - 828 WP_129393214.1 ABC transporter permease -
C2E19_RS14045 3061942..3062739 - 798 WP_129393217.1 ATP-binding cassette domain-containing protein -
C2E19_RS14050 3062736..3063599 - 864 WP_129393220.1 putative selenate ABC transporter substrate-binding protein -
C2E19_RS14060 3064004..3064618 - 615 WP_129393223.1 HD domain-containing protein Toxin
C2E19_RS14065 3064694..3065251 - 558 WP_129393226.1 helix-turn-helix domain-containing protein Antitoxin
C2E19_RS14070 3065325..3065726 - 402 WP_129393229.1 RidA family protein -
C2E19_RS14075 3065841..3066734 + 894 WP_129393232.1 LysR family transcriptional regulator -
C2E19_RS14080 3066857..3068017 + 1161 WP_129393235.1 radical SAM/SPASM domain-containing protein -
C2E19_RS14085 3067966..3068874 - 909 WP_129393238.1 LysR family transcriptional regulator -
C2E19_RS14090 3068986..3070038 + 1053 WP_129393241.1 agmatine deiminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-172)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 205 a.a.        Molecular weight: 22979.08 Da        Isoelectric Point: 4.6887

>T97639 WP_129393223.1 NZ_CP027218:c3064618-3064004 [Pseudomonas sp. DTU12.3]
MNLEKLSGRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAIVFADELAGLDLLKVLKMCVIHDLGEAINGDIP
AVDQAAFPAKGEQERNDLLLLTRSLDETVRNEILALWDDYENALSAEAKAVKALDKLETLLQHTQGQNPADFDYRFNLTY
GIKHTSTEPVFAALRALIDQDTRKRMNMNLTIRNEQPDDIDTIA

Download         Length: 615 bp

>T97639 NZ_CP027218:c3064618-3064004 [Pseudomonas sp. DTU12.3]
ATGAACCTCGAAAAACTCAGTGGACGCCTCGAGTTCCTGCGTGAAGCGGAAAAACTCAAGGATGTCCTCAGAAGCGCACA
CACTTCCAGCGGTCGCACCGAGAGCACCGCCGAACACAGCTGGCGTCTGTGCCTGATGGCGATCGTCTTCGCCGATGAAC
TGGCCGGTCTCGACCTGCTTAAAGTGCTCAAGATGTGTGTCATTCACGACTTGGGCGAGGCGATCAACGGCGACATCCCG
GCGGTCGATCAAGCCGCATTCCCCGCCAAGGGCGAACAGGAGCGTAACGACCTCCTGCTACTGACTCGCTCACTCGACGA
GACGGTGAGAAACGAAATCCTCGCGTTGTGGGACGACTACGAAAATGCCCTGTCTGCCGAGGCCAAAGCAGTCAAGGCGC
TGGACAAACTCGAGACCCTGCTGCAACACACTCAAGGGCAGAACCCGGCCGATTTCGACTACCGCTTCAATCTGACTTAC
GGCATCAAACACACCAGTACCGAGCCGGTGTTCGCAGCGTTGCGAGCGCTTATCGATCAGGACACCCGAAAAAGGATGAA
CATGAACCTGACTATTCGCAACGAACAACCCGACGACATCGACACCATCGCTTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20397.60 Da        Isoelectric Point: 8.1707

>AT97639 WP_129393226.1 NZ_CP027218:c3065251-3064694 [Pseudomonas sp. DTU12.3]
MSVSLLKPALPGIAMRRWRLLHRVKQSHAAQMFNVTQSTISRWESGVLAMDPAAHLQLEQLLAARLDTAADQALARLVCD
SARPVHLVCDLTHRLLACSASRAAQFTSPLSELLGQSLWRFVTPEIASNELALDTLGWRELQAPPALQFITGSNDSDLVP
IRQSLCRWTRIPLSDGTAARLVETL

Download         Length: 558 bp

>AT97639 NZ_CP027218:c3065251-3064694 [Pseudomonas sp. DTU12.3]
ATGTCAGTTTCATTGCTCAAACCTGCCCTCCCCGGCATCGCCATGCGTCGTTGGCGCTTGTTGCATCGCGTCAAGCAAAG
CCACGCCGCGCAGATGTTCAATGTCACCCAATCGACTATTTCCCGCTGGGAAAGCGGCGTGCTGGCGATGGATCCGGCGG
CACACTTACAGCTTGAGCAACTGCTGGCCGCGCGTCTCGACACGGCTGCCGACCAGGCCCTCGCCCGGCTGGTCTGCGAC
AGCGCACGCCCGGTGCACCTGGTCTGCGACCTGACCCACCGTTTGCTGGCCTGCTCTGCGTCCCGCGCCGCACAGTTCAC
CAGCCCGCTGAGCGAATTGCTCGGGCAATCGCTGTGGCGTTTCGTCACGCCAGAAATCGCCAGCAACGAACTGGCACTCG
ACACCTTGGGCTGGCGCGAACTGCAGGCACCACCGGCGCTGCAATTCATCACCGGCAGCAACGACTCCGACCTCGTGCCA
ATTCGCCAGAGCCTGTGCCGCTGGACACGCATTCCCCTGTCCGACGGTACGGCGGCGCGGCTGGTCGAGACACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References