Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2956038..2956183 Replicon chromosome
Accession NZ_CP027189
Organism Klebsiella pneumoniae strain KPHS1249

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2956074..2956176 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2956038..2956183 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5Z24_RS14625 2951168..2953228 + 2061 WP_004151449.1 oligopeptidase B -
C5Z24_RS14630 2953232..2953891 - 660 WP_002911407.1 exodeoxyribonuclease X -
C5Z24_RS14635 2953970..2954200 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C5Z24_RS14640 2954313..2954687 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C5Z24_RS14645 2954691..2955560 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
C5Z24_RS14650 2955577..2955915 + 339 WP_002911404.1 YebY family protein -
- 2956038..2956183 - 146 - - Antitoxin
- 2956074..2956176 + 103 - - Toxin
C5Z24_RS27125 2956551..2956694 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C5Z24_RS14660 2956799..2957767 - 969 WP_014907334.1 VirK/YbjX family protein -
C5Z24_RS14665 2957924..2958577 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C5Z24_RS14670 2958574..2958765 - 192 WP_002911395.1 YebW family protein -
C5Z24_RS14675 2958863..2959102 - 240 WP_002911393.1 YebV family protein -
C5Z24_RS14680 2959218..2960651 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97598 NZ_CP027189:2956074-2956176 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97598 NZ_CP027189:c2956183-2956038 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References