Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
Location | 7199683..7200188 | Replicon | chromosome |
Accession | NZ_CP027172 | ||
Organism | Pseudomonas aeruginosa strain AR_0353 |
Toxin (Protein)
Gene name | parE | Uniprot ID | V6A7K8 |
Locus tag | CSB90_RS35010 | Protein ID | WP_003083773.1 |
Coordinates | 7199907..7200188 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A1C7BDS9 |
Locus tag | CSB90_RS35005 | Protein ID | WP_003083775.1 |
Coordinates | 7199683..7199910 (+) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CSB90_RS34980 | 7194701..7196194 | + | 1494 | WP_003101230.1 | CoA-acylating methylmalonate-semialdehyde dehydrogenase | - |
CSB90_RS34985 | 7196363..7197790 | + | 1428 | WP_003083784.1 | GABA permease | - |
CSB90_RS34990 | 7197872..7198213 | - | 342 | WP_003101229.1 | alkylphosphonate utilization protein | - |
CSB90_RS34995 | 7198286..7198786 | - | 501 | WP_003128336.1 | LEA type 2 family protein | - |
CSB90_RS35000 | 7198887..7199507 | + | 621 | WP_003101226.1 | hypothetical protein | - |
CSB90_RS35005 | 7199683..7199910 | + | 228 | WP_003083775.1 | CopG family ribbon-helix-helix protein | Antitoxin |
CSB90_RS35010 | 7199907..7200188 | + | 282 | WP_003083773.1 | type II toxin-antitoxin system toxin ParE | Toxin |
CSB90_RS35015 | 7200488..7201396 | + | 909 | WP_003083769.1 | LysR family transcriptional regulator | - |
CSB90_RS35020 | 7201428..7201814 | - | 387 | WP_003083767.1 | aegerolysin family protein | - |
CSB90_RS35025 | 7202018..7202752 | - | 735 | WP_003128333.1 | GntR family transcriptional regulator | - |
CSB90_RS35030 | 7202853..7203539 | - | 687 | WP_003083762.1 | FadR family transcriptional regulator | - |
CSB90_RS35035 | 7203588..7204937 | - | 1350 | WP_003119513.1 | C4-dicarboxylate transporter DctA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10462.19 Da Isoelectric Point: 10.0435
>T97551 WP_003083773.1 NZ_CP027172:7199907-7200188 [Pseudomonas aeruginosa]
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
MSLKWTRKAAADLDAIYDHYVVLIGPEKALKAVQDIVEQVKPLQQVANQGAGRPSEVPGVRTLTLERWPFSAPFRVKGKE
IQILRIDRVEITP
Download Length: 282 bp
>T97551 NZ_CP027172:7199907-7200188 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTAA
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8556.58 Da Isoelectric Point: 5.5740
>AT97551 WP_003083775.1 NZ_CP027172:7199683-7199910 [Pseudomonas aeruginosa]
MSTVVSFRADDALVAALDELARATHRDRPYHLRQALAQYLERQQWQVAAIDEGLADANAGRLLEHTEIEKRWGLQ
MSTVVSFRADDALVAALDELARATHRDRPYHLRQALAQYLERQQWQVAAIDEGLADANAGRLLEHTEIEKRWGLQ
Download Length: 228 bp
>AT97551 NZ_CP027172:7199683-7199910 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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