Detailed information of TA system TA097537

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 10557..11227
• Replicon: plasmid unnamed1
• Accession: NZ_CP027168
• Organism: Pseudomonas aeruginosa strain AR_0356

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: CSB93_RS01145
• Protein ID: WP_105446699.1
• Coordinates: 10557..10994 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: CSB93_RS01150
• Protein ID: WP_105446700.1
• Coordinates: 10991..11227 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSB93_RS01105	5690..6034	-	345	WP_105446694.1	hypothetical protein	-
CSB93_RS01110	6095..6598	-	504	WP_105446695.1	hypothetical protein	-
CSB93_RS01115	6615..7043	-	429	WP_105446696.1	hypothetical protein	-
CSB93_RS01120	7099..7935	-	837	WP_015272400.1	DUF945 domain-containing protein	-
CSB93_RS01125	8616..8876	-	261	WP_058565745.1	hypothetical protein	-
CSB93_RS01130	8888..9196	-	309	WP_058565746.1	hypothetical protein	-
CSB93_RS01135	9186..9998	-	813	WP_105446697.1	3'-5' exonuclease	-
CSB93_RS01140	10014..10550	-	537	WP_105446698.1	hypothetical protein	-
CSB93_RS01145	10557..10994	-	438	WP_105446699.1	type II toxin-antitoxin system VapC family toxin	Toxin
CSB93_RS01150	10991..11227	-	237	WP_105446700.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CSB93_RS01155	11237..11662	-	426	WP_105446701.1	DUF192 domain-containing protein	-
CSB93_RS01160	11997..12302	-	306	WP_204100709.1	hypothetical protein	-
CSB93_RS01165	12330..12980	-	651	WP_058565752.1	DNA-binding protein	-
CSB93_RS01170	13572..14726	-	1155	WP_105446702.1	replication initiator protein A	-
CSB93_RS01175	14713..15330	-	618	WP_105446703.1	recombinase family protein	-
CSB93_RS35540	15345..15686	-	342	WP_123809515.1	hypothetical protein	-
CSB93_RS01180	15855..16115	-	261	WP_105446704.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..57053	57053

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 21505.80 Da
• Isoelectric Point: 5.5500

>T97537 WP_105446699.1 NZ_CP027168:c10994-10557 [Pseudomonas aeruginosa]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 438 bp

>T97537 NZ_CP027168:c10994-10557 [Pseudomonas aeruginosa]
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Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 11644.97 Da
• Isoelectric Point: 5.5500

>AT97537 WP_105446700.1 NZ_CP027168:c11227-10991 [Pseudomonas aeruginosa]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 237 bp

>AT97537 NZ_CP027168:c11227-10991 [Pseudomonas aeruginosa]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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