Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2335768..2335913 Replicon chromosome
Accession NZ_CP027160
Organism Klebsiella pneumoniae strain AR_0361

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2335775..2335877 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2335768..2335913 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB98_RS12625 2331300..2332733 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CSB98_RS12630 2332849..2333088 + 240 WP_002911393.1 YebV family protein -
CSB98_RS12635 2333186..2333377 + 192 WP_002911395.1 YebW family protein -
CSB98_RS12640 2333374..2334027 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
CSB98_RS12645 2334184..2335152 + 969 WP_004151446.1 VirK/YbjX family protein -
CSB98_RS29395 2335257..2335400 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2335768..2335913 + 146 - - Antitoxin
- 2335775..2335877 - 103 - - Toxin
CSB98_RS12655 2336036..2336374 - 339 WP_002911404.1 YebY family protein -
CSB98_RS12660 2336391..2337260 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CSB98_RS12665 2337264..2337638 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CSB98_RS12670 2337751..2337981 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CSB98_RS12675 2338060..2338719 + 660 WP_002911407.1 exodeoxyribonuclease X -
CSB98_RS12680 2338723..2340783 - 2061 WP_032422099.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97507 NZ_CP027160:c2335877-2335775 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97507 NZ_CP027160:2335768-2335913 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References