Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4171473..4171618 Replicon chromosome
Accession NZ_CP027146
Organism Klebsiella pneumoniae strain AR_0363

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4171509..4171611 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4171473..4171618 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC00_RS20960 4166603..4168663 + 2061 WP_004151449.1 oligopeptidase B -
CSC00_RS20965 4168667..4169326 - 660 WP_002911407.1 exodeoxyribonuclease X -
CSC00_RS20970 4169405..4169635 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CSC00_RS20975 4169748..4170122 + 375 WP_023286640.1 CopC domain-containing protein YobA -
CSC00_RS20980 4170126..4170995 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
CSC00_RS20985 4171012..4171350 + 339 WP_016529031.1 YebY family protein -
- 4171473..4171618 - 146 - - Antitoxin
- 4171509..4171611 + 103 - - Toxin
CSC00_RS31285 4171985..4172128 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CSC00_RS20995 4172233..4173201 - 969 WP_074194451.1 VirK/YbjX family protein -
CSC00_RS21000 4173358..4174011 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
CSC00_RS21005 4174008..4174199 - 192 WP_002911395.1 YebW family protein -
CSC00_RS21010 4174297..4174536 - 240 WP_002911393.1 YebV family protein -
CSC00_RS21015 4174652..4176085 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97492 NZ_CP027146:4171509-4171611 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97492 NZ_CP027146:c4171618-4171473 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References