Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4738698..4739260 Replicon chromosome
Accession NZ_CP027114
Organism Gordonia alkanivorans strain YC-RL2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C5O27_RS21515 Protein ID WP_006360630.1
Coordinates 4738698..4738988 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C5O27_RS21520 Protein ID WP_035753144.1
Coordinates 4738985..4739260 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5O27_RS21500 4735474..4736235 - 762 WP_127963622.1 IclR family transcriptional regulator -
C5O27_RS21505 4736386..4737660 + 1275 WP_127963623.1 aldolase -
C5O27_RS21510 4737717..4738529 + 813 WP_127963917.1 (S)-ureidoglycine aminohydrolase -
C5O27_RS21515 4738698..4738988 - 291 WP_006360630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C5O27_RS21520 4738985..4739260 - 276 WP_035753144.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C5O27_RS21525 4739441..4739659 - 219 WP_127963624.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
C5O27_RS21530 4739741..4740463 - 723 WP_127963625.1 Asp/Glu/hydantoin racemase -
C5O27_RS21535 4740484..4742037 - 1554 WP_208651398.1 cytosine permease -
C5O27_RS21540 4742287..4743681 + 1395 WP_127963626.1 allantoinase AllB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10875.35 Da        Isoelectric Point: 10.2270

>T97331 WP_006360630.1 NZ_CP027114:c4738988-4738698 [Gordonia alkanivorans]
MNDAPTDSPAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLGGLHSARRGDYRVLLRIDDPNH
TIVVVRIDHRAHAYRT

Download         Length: 291 bp

>T97331 NZ_CP027114:c4738988-4738698 [Gordonia alkanivorans]
ATGAACGACGCTCCGACAGACTCGCCCGCCCCCTACCGGGTCGAGGTCGCATCCCCAGCTCGCCGCGACCTTCAACGCCT
TCCATCCCGGATCGTCCACGCCGTCATCGAGTTCATCTCCGGACCCCTCGCCGAGAACCCGCACCGGCTCAGCAAACCGC
TGCGCGACGACCTCGGAGGCCTCCACAGCGCCCGCCGCGGTGACTACCGGGTCCTGCTGCGCATCGACGACCCGAACCAC
ACCATCGTCGTCGTCAGAATCGACCACCGTGCCCACGCATATCGCACCTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9750.93 Da        Isoelectric Point: 4.6221

>AT97331 WP_035753144.1 NZ_CP027114:c4739260-4738985 [Gordonia alkanivorans]
MTTVPLGEAKDKLSALIDSAETTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGLRDDVATADAEYAAGHTVSID
DLRAEHGLPPK

Download         Length: 276 bp

>AT97331 NZ_CP027114:c4739260-4738985 [Gordonia alkanivorans]
ATGACTACAGTGCCACTCGGCGAGGCCAAGGACAAGCTCTCCGCGCTCATCGACAGCGCCGAGACCACGCACGACATCAT
CACGATCACCAAGCACGGCAAACCCGCCGCGGTGCTGATGTCGGCCGACGACCTCGAATCGTTGCACGAGACGATCTACT
GGCTCTCACGTGCCGGTCTCCGCGACGACGTCGCCACCGCCGACGCCGAGTACGCCGCCGGCCACACCGTCTCCATCGAC
GACCTGCGCGCCGAACACGGCCTGCCGCCGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References