Detailed information of TA system TA097330

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 3592583..3593145
• Replicon: chromosome
• Accession: NZ_CP027114
• Organism: Gordonia alkanivorans strain YC-RL2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C5O27_RS16360
• Protein ID: WP_127963154.1
• Coordinates: 3592583..3592873 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C5O27_RS16365
• Protein ID: WP_127963155.1
• Coordinates: 3592870..3593145 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5O27_RS16335	3587603..3589180	-	1578	WP_127963150.1	ParB N-terminal domain-containing protein	-
C5O27_RS16340	3589279..3589557	-	279	WP_127963151.1	hypothetical protein	-
C5O27_RS16345	3589585..3589812	-	228	WP_127963152.1	hypothetical protein	-
C5O27_RS16350	3590342..3590677	-	336	WP_127963861.1	hypothetical protein	-
C5O27_RS16355	3591141..3592409	-	1269	WP_127963153.1	hypothetical protein	-
C5O27_RS16360	3592583..3592873	-	291	WP_127963154.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C5O27_RS16365	3592870..3593145	-	276	WP_127963155.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C5O27_RS16370	3593473..3594420	+	948	WP_127963156.1	ABC transporter permease	-
C5O27_RS16375	3594437..3594814	-	378	WP_127963157.1	SRPBCC family protein	-
C5O27_RS16380	3595209..3596042	-	834	WP_127963158.1	DUF4436 family protein	-
C5O27_RS16385	3596293..3596682	+	390	WP_035752373.1	DUF1304 domain-containing protein	-
C5O27_RS16390	3596716..3597363	-	648	WP_127963159.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3510308..3594853	84545

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (14-94)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10865.31 Da
• Isoelectric Point: 9.7360

>T97330 WP_127963154.1 NZ_CP027114:c3592873-3592583 [Gordonia alkanivorans]
MSDAPPDSSGPYRVEVASPARRDLGRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLTDLHSARRGDYRILLRIDDPNH
TIVVVRIDHRAHAYRT

Nucleotide

• Length: 291 bp

>T97330 NZ_CP027114:c3592873-3592583 [Gordonia alkanivorans]
ATGAGCGACGCTCCGCCAGACTCGTCCGGCCCGTACCGGGTCGAGGTCGCCTCCCCAGCCCGCCGCGACCTCGGGCGACT
CCCATCCCGGATCGTTCACGCCGTCATCGAATTCATCTCCGGGCCCCTCGCCGAGAACCCTCACCGACTTAGCAAGCCGC
TACGCGACGACCTCACCGACCTTCACAGCGCCCGCCGAGGTGACTATCGGATCCTGCTCCGCATCGACGACCCCAACCAC
ACCATCGTCGTTGTCAGAATCGACCACCGCGCCCACGCCTATCGCACCTAA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9784.96 Da
• Isoelectric Point: 4.6221

>AT97330 WP_127963155.1 NZ_CP027114:c3593145-3592870 [Gordonia alkanivorans]
MTTVPLGEAKDKLSALIDSAETTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADTEYAAGHTVSID
DLRAEHGMPPK

Nucleotide

• Length: 276 bp

>AT97330 NZ_CP027114:c3593145-3592870 [Gordonia alkanivorans]
ATGACGACAGTGCCACTCGGCGAAGCCAAAGACAAGCTCTCAGCGCTCATCGACAGCGCCGAAACCACGCACGACATCAT
CACGATCACCAAGCACGGCAAACCCGCCGCGGTGCTGATGTCGGCCGACGACCTCGAATCGCTCCACGAGACGATCTACT
GGCTCTCACGTGCCGGTGTCCGCGACGACGTCGCTACCGCCGACACCGAATACGCCGCCGGCCACACCGTCTCCATCGAC
GACCTGCGCGCCGAACACGGCATGCCGCCGAAATGA