Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2662617..2662888 Replicon chromosome
Accession NZ_CP027105
Organism Escherichia coli strain RM14721

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2662655..2662758 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2662617..2662888 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5097_RS14150 2659774..2661213 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C5097_RS14155 2661331..2661567 + 237 WP_001338166.1 DUF1480 family protein -
C5097_RS14160 2661672..2661863 + 192 WP_001338167.1 YebW family protein -
C5097_RS14165 2661864..2662520 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2662617..2662888 + 272 - - Antitoxin
- 2662655..2662758 - 104 - - Toxin
C5097_RS14170 2662916..2663257 - 342 WP_072145846.1 YebY family protein -
C5097_RS14175 2663270..2664142 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
C5097_RS14180 2664146..2664520 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C5097_RS14185 2664659..2664889 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C5097_RS14190 2664991..2665647 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C5097_RS14195 2665671..2666333 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T97273 NZ_CP027105:c2662758-2662655 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT97273 NZ_CP027105:2662617-2662888 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References