Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019253..2019398 | Replicon | chromosome |
| Accession | NZ_CP027068 | ||
| Organism | Klebsiella pneumoniae strain WCHKP8F4 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2019289..2019391 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019253..2019398 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B7D38_RS11325 | 2014383..2016443 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| B7D38_RS11330 | 2016447..2017106 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| B7D38_RS11335 | 2017185..2017415 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| B7D38_RS11340 | 2017528..2017902 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| B7D38_RS11345 | 2017906..2018775 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| B7D38_RS11350 | 2018789..2019130 | + | 342 | WP_015874944.1 | YebY family protein | - |
| - | 2019253..2019398 | - | 146 | - | - | Antitoxin |
| - | 2019289..2019391 | + | 103 | - | - | Toxin |
| B7D38_RS11355 | 2019433..2019624 | - | 192 | WP_004175432.1 | hypothetical protein | - |
| B7D38_RS11360 | 2020014..2020904 | - | 891 | WP_085353163.1 | VirK/YbjX family protein | - |
| B7D38_RS11365 | 2021139..2021792 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| B7D38_RS11370 | 2021789..2021980 | - | 192 | WP_002911395.1 | YebW family protein | - |
| B7D38_RS11375 | 2022078..2022317 | - | 240 | WP_002911393.1 | YebV family protein | - |
| B7D38_RS11380 | 2022433..2023866 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T97225 NZ_CP027068:2019289-2019391 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT97225 NZ_CP027068:c2019398-2019253 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
