Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1891336..1891480 Replicon chromosome
Accession NZ_CP027064
Organism Klebsiella variicola strain WCHKV030666

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1891372..1891474 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1891336..1891480 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ71_RS10520 1886466..1888526 + 2061 WP_012541258.1 oligopeptidase B -
CLQ71_RS10525 1888530..1889189 - 660 WP_012541259.1 exodeoxyribonuclease X -
CLQ71_RS10530 1889268..1889498 - 231 WP_012541260.1 DNA polymerase III subunit theta -
CLQ71_RS10535 1889612..1889986 + 375 WP_012541261.1 CopC domain-containing protein YobA -
CLQ71_RS10540 1889990..1890859 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
CLQ71_RS10545 1890876..1891214 + 339 WP_008804271.1 YebY family protein -
- 1891336..1891480 - 145 - - Antitoxin
- 1891372..1891474 + 103 - - Toxin
CLQ71_RS10555 1891859..1892002 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
CLQ71_RS10560 1892106..1893095 - 990 WP_032691211.1 VirK/YbjX family protein -
CLQ71_RS10565 1893231..1893884 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
CLQ71_RS10570 1893881..1894072 - 192 WP_002911395.1 YebW family protein -
CLQ71_RS10575 1894170..1894409 - 240 WP_002911393.1 YebV family protein -
CLQ71_RS10580 1894525..1895958 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97203 NZ_CP027064:1891372-1891474 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT97203 NZ_CP027064:c1891480-1891336 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References