Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 635633..635778 Replicon chromosome
Accession NZ_CP027053
Organism Klebsiella pneumoniae strain 2_GR_12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 635669..635771 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 635633..635778 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6D68_RS03025 630763..632823 + 2061 WP_032422099.1 oligopeptidase B -
A6D68_RS03030 632827..633486 - 660 WP_002911407.1 exodeoxyribonuclease X -
A6D68_RS03035 633565..633795 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A6D68_RS03040 633908..634282 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A6D68_RS03045 634286..635155 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
A6D68_RS03050 635172..635510 + 339 WP_002911404.1 YebY family protein -
- 635633..635778 - 146 - - Antitoxin
- 635669..635771 + 103 - - Toxin
A6D68_RS31005 636146..636289 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A6D68_RS03060 636394..637362 - 969 WP_004151446.1 VirK/YbjX family protein -
A6D68_RS03065 637519..638172 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
A6D68_RS03070 638169..638360 - 192 WP_002911395.1 YebW family protein -
A6D68_RS03075 638458..638697 - 240 WP_002911393.1 YebV family protein -
A6D68_RS03080 638813..640246 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97169 NZ_CP027053:635669-635771 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97169 NZ_CP027053:c635778-635633 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References