Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1923058..1923203 Replicon chromosome
Accession NZ_CP027042
Organism Klebsiella pneumoniae strain 1_GR_13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1923094..1923196 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1923058..1923203 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6D67_RS09545 1918188..1920248 + 2061 WP_004151449.1 oligopeptidase B -
A6D67_RS09550 1920252..1920911 - 660 WP_002911407.1 exodeoxyribonuclease X -
A6D67_RS09555 1920990..1921220 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A6D67_RS09560 1921333..1921707 + 375 WP_060577972.1 CopC domain-containing protein YobA -
A6D67_RS09565 1921711..1922580 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
A6D67_RS09570 1922597..1922935 + 339 WP_002911404.1 YebY family protein -
- 1923058..1923203 - 146 - - Antitoxin
- 1923094..1923196 + 103 - - Toxin
A6D67_RS29160 1923572..1923715 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
A6D67_RS09580 1923820..1924788 - 969 WP_014907334.1 VirK/YbjX family protein -
A6D67_RS09585 1924945..1925598 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
A6D67_RS09590 1925595..1925786 - 192 WP_002911395.1 YebW family protein -
A6D67_RS09595 1925884..1926123 - 240 WP_002911393.1 YebV family protein -
A6D67_RS09600 1926239..1927672 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97133 NZ_CP027042:1923094-1923196 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97133 NZ_CP027042:c1923203-1923058 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References