Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4605018..4605163 Replicon chromosome
Accession NZ_CP027036
Organism Klebsiella pneumoniae strain 16_GR_13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4605025..4605127 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4605018..4605163 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6D82_RS23205 4600550..4601983 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A6D82_RS23210 4602099..4602338 + 240 WP_002911393.1 YebV family protein -
A6D82_RS23215 4602436..4602627 + 192 WP_002911395.1 YebW family protein -
A6D82_RS23220 4602624..4603277 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
A6D82_RS23225 4603434..4604402 + 969 WP_004151446.1 VirK/YbjX family protein -
A6D82_RS30810 4604507..4604650 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4605018..4605163 + 146 - - Antitoxin
- 4605025..4605127 - 103 - - Toxin
A6D82_RS23235 4605286..4605624 - 339 WP_016529031.1 YebY family protein -
A6D82_RS23240 4605641..4606510 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A6D82_RS23245 4606514..4606888 - 375 WP_004151448.1 CopC domain-containing protein YobA -
A6D82_RS23250 4607001..4607231 + 231 WP_002911406.1 DNA polymerase III subunit theta -
A6D82_RS23255 4607310..4607969 + 660 WP_032425085.1 exodeoxyribonuclease X -
A6D82_RS23260 4607973..4610033 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97118 NZ_CP027036:c4605127-4605025 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT97118 NZ_CP027036:4605018-4605163 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References