97048

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 617120..618467 Replicon chromosome
Accession NZ_CP027031
Organism Vibrio vulnificus strain FORC_077

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag FORC77_RS18385 Protein ID WP_015727856.1
Coordinates 617526..618467 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A3Q0KXE1
Locus tag FORC77_RS18380 Protein ID WP_011081161.1
Coordinates 617120..617524 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC77_RS18360 612317..612775 + 459 WP_011081157.1 hypothetical protein -
FORC77_RS18365 612965..613711 + 747 WP_131070284.1 carbon-nitrogen hydrolase family protein -
FORC77_RS18370 614210..614974 + 765 WP_131070285.1 nucleotidyltransferase domain-containing protein -
FORC77_RS18375 615027..616787 - 1761 WP_118894274.1 ABC transporter ATP-binding protein/permease -
FORC77_RS18380 617120..617524 + 405 WP_011081161.1 hypothetical protein Antitoxin
FORC77_RS18385 617526..618467 + 942 WP_015727856.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FORC77_RS18390 618854..620440 + 1587 WP_045622347.1 AAA family ATPase -
FORC77_RS18395 620425..621456 + 1032 WP_118894275.1 DNA helicase UvrD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36057.46 Da        Isoelectric Point: 5.3076

>T97048 WP_015727856.1 NZ_CP027031:617526-618467 [Vibrio vulnificus]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKGVRKAWVNEIEQAITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Download         Length: 942 bp

>T97048 NZ_CP027031:617526-618467 [Vibrio vulnificus]
ATGAACGCACTAAAACAACAATTTCTTGAGGTTTCCGACGCGCTTGAGCTCGGAAATCCTGCCATCATTGAAAAAGATTT
CTGGGTCGTCGCCTTACTTGCCGAGCTAGCAAAAGTTTCTCCTGAATATCATCAAATGGTCTTTTCCGGCGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCGTTTGATGAA
CTGAGTCGAGCAAAAAAGAAAGGCGTTAGAAAGGCATGGGTTAACGAGATTGAACAGGCGATCACTCATTCAGAACGATT
TACCGTTGAAACGCGATCTGTGCGAGATGAGTACCGTTACGTTGAGTTTGAACTCAGATATCCGCAACAGTTTAGTCAAG
TTCCCTGTCTTCGTCCCATCATTAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTGGAGTCGCGCAGCATTCAA
TCATTGGTTGCAGAGTTGTACCAACAACCGCACGAAGTGAGTTCATTTGATTGCGTCTCTGTCTATGCCACATTGGTTGA
AAAAATCATTTCGATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTCTAGTTCGCC
ATATCTACGATGTGCATTGCATAACAAAGCTCACAATGTCTGAACTCAACTCGATTGACGGCCTATTCAAAGCGGTCTTG
GAAGAAGATATTGCCCGCTTTGGCAATCAACATGCAGAGTTTGTTGCCAACCCTAAACAAGAGCTACAACTTGGCCTCAA
AGAGCTTGAGGAAAATCCCATTTTCCGCCAACGTTTTCAGGACTTTGTCACACCAATGGTGTTTAACACTGAGCCCCATG
ATTTTGATACCTGCTTTGCCTCATTCAAGCGAATTGCAGCGTCGCTAATTGAAAAAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15175.47 Da        Isoelectric Point: 10.6526

>AT97048 WP_011081161.1 NZ_CP027031:617120-617524 [Vibrio vulnificus]
MTAVDRIYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT97048 NZ_CP027031:617120-617524 [Vibrio vulnificus]
ATGACAGCAGTAGACCGCATTTATCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGACGGATT
TGCAAGTTACGACCAAATAGGTCGGGCATTGAGGCAGCTTGTACAGCAAGGGGAGCTAATGAAGCTTGGCTATGGTTTGT
ATACCAAAGCAAGAATCAATAGCCTCACTGGTAAGCCTATGCCTACCAATCCAGGTGGTACCGATGCTCTTGTGCGTGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAAATGGATAGTCTATCGCAACAAAGTCTTTCAGGTGCGAGTACCCAAATTCC
ATCCTCTGTTCACTATTCATGGAACCCAAAACAGTTTAATCGCAAACTGGTGGTTGGTAGCCGTGTGCTGAACTTGCCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q0KXE1

References