Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3543247..3543972 Replicon chromosome
Accession NZ_CP026985
Organism Pectobacterium parmentieri strain IFB5619

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag C5E25_RS16485 Protein ID WP_103808442.1
Coordinates 3543247..3543567 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag C5E25_RS16490 Protein ID WP_103808441.1
Coordinates 3543637..3543972 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5E25_RS16465 3539090..3540409 + 1320 WP_103808725.1 site-specific integrase -
C5E25_RS16470 3540481..3541530 - 1050 WP_103808726.1 macro domain-containing protein -
C5E25_RS16475 3541544..3542191 - 648 WP_103808727.1 DUF4433 domain-containing protein -
C5E25_RS16480 3542296..3543129 - 834 WP_121247172.1 DUF4942 domain-containing protein -
C5E25_RS16485 3543247..3543567 - 321 WP_103808442.1 TA system toxin CbtA family protein Toxin
C5E25_RS16490 3543637..3543972 - 336 WP_103808441.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
C5E25_RS16495 3544009..3544482 - 474 WP_121247002.1 DNA repair protein RadC -
C5E25_RS16500 3544567..3544800 - 234 WP_040034648.1 membrane protein -
C5E25_RS16505 3544818..3545291 - 474 WP_103808732.1 hypothetical protein -
C5E25_RS16510 3545327..3545896 - 570 Protein_3166 hypothetical protein -
C5E25_RS16515 3546078..3546776 - 699 WP_121247005.1 DeoR family transcriptional regulator -
C5E25_RS16520 3547146..3548021 - 876 WP_103808734.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12035.73 Da        Isoelectric Point: 4.7768

>T96988 WP_103808442.1 NZ_CP026985:c3543567-3543247 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T96988 NZ_CP026985:c3543567-3543247 [Pectobacterium parmentieri]
ATGCAAACATCACCGGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCTATAGCCGTCTGGCAGCAACTACTGAC
TTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACACCATTCTGTGAGGAAAACGTGATTCAGGAGCATATCG
ATGCTGGCATCACGCTGGCCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCGCCGTTTCTTACCGCCGTTGATGTTCTCCGTGCTAGACGTGCAACGGGCTTGCTCAAGGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12643.32 Da        Isoelectric Point: 5.5351

>AT96988 WP_103808441.1 NZ_CP026985:c3543972-3543637 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAITPRFGARLVQEGHRLHYLEDRASIVGTFSEMEAHHLEEIFPELIKQLEQKLRSGELNPRQRGCVT
LYCNEWTCEADTLGSFGYVYIVIYPTSAATH

Download         Length: 336 bp

>AT96988 NZ_CP026985:c3543972-3543637 [Pectobacterium parmentieri]
ATGCCATCATCGGATACCCCGGAGTGGGGATTAAAATGTGCCATCACGCCGCGATTCGGAGCCAGGCTGGTCCAGGAAGG
ACACCGCCTGCATTATCTGGAAGACCGGGCCAGCATTGTCGGTACGTTCAGCGAAATGGAAGCCCACCATCTGGAAGAGA
TCTTTCCTGAGCTGATTAAGCAGTTGGAACAAAAACTGCGCTCGGGTGAGTTGAATCCCCGTCAGCGGGGTTGCGTCACG
CTGTATTGTAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTTTTGGTTATGTATATATTGTTATTTATCCCACTTC
TGCAGCAACACACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References