Detailed information of TA system TA096985

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1457339..1458064
• Replicon: chromosome
• Accession: NZ_CP026985
• Organism: Pectobacterium parmentieri strain IFB5619

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: C5E25_RS06910
• Protein ID: WP_103808442.1
• Coordinates: 1457339..1457659 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E25_RS06915
• Protein ID: WP_103808441.1
• Coordinates: 1457729..1458064 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E25_RS06885	1452542..1452832	-	291	WP_014699065.1	transposase	-
C5E25_RS06890	1452898..1453227	+	330	Protein_1321	IS30 family transposase	-
C5E25_RS06895	1453401..1454030	-	630	WP_103808445.1	hypothetical protein	-
C5E25_RS06900	1454461..1455675	-	1215	WP_103808444.1	tyrosine-type recombinase/integrase	-
C5E25_RS06905	1456388..1457221	-	834	WP_103808443.1	DUF4942 domain-containing protein	-
C5E25_RS06910	1457339..1457659	-	321	WP_103808442.1	TA system toxin CbtA family protein	Toxin
C5E25_RS06915	1457729..1458064	-	336	WP_103808441.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E25_RS06920	1458101..1458574	-	474	WP_121247002.1	DNA repair protein RadC	-
C5E25_RS06925	1458659..1458892	-	234	WP_040034648.1	membrane protein	-
C5E25_RS06930	1458910..1459383	-	474	WP_103808732.1	hypothetical protein	-
C5E25_RS06935	1459419..1459988	-	570	Protein_1330	hypothetical protein	-
C5E25_RS06940	1460170..1460868	-	699	WP_121247005.1	DeoR family transcriptional regulator	-
C5E25_RS06945	1461238..1462113	-	876	WP_103808734.1	GTPase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1450273..1475803	25530

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12035.73 Da
• Isoelectric Point: 4.7768

>T96985 WP_103808442.1 NZ_CP026985:c1457659-1457339 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T96985 NZ_CP026985:c1457659-1457339 [Pectobacterium parmentieri]
ATGCAAACATCACCGGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCTATAGCCGTCTGGCAGCAACTACTGAC
TTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACACCATTCTGTGAGGAAAACGTGATTCAGGAGCATATCG
ATGCTGGCATCACGCTGGCCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCGCCGTTTCTTACCGCCGTTGATGTTCTCCGTGCTAGACGTGCAACGGGCTTGCTCAAGGCATA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12643.32 Da
• Isoelectric Point: 5.5351

>AT96985 WP_103808441.1 NZ_CP026985:c1458064-1457729 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAITPRFGARLVQEGHRLHYLEDRASIVGTFSEMEAHHLEEIFPELIKQLEQKLRSGELNPRQRGCVT
LYCNEWTCEADTLGSFGYVYIVIYPTSAATH

Nucleotide

• Length: 336 bp

>AT96985 NZ_CP026985:c1458064-1457729 [Pectobacterium parmentieri]
ATGCCATCATCGGATACCCCGGAGTGGGGATTAAAATGTGCCATCACGCCGCGATTCGGAGCCAGGCTGGTCCAGGAAGG
ACACCGCCTGCATTATCTGGAAGACCGGGCCAGCATTGTCGGTACGTTCAGCGAAATGGAAGCCCACCATCTGGAAGAGA
TCTTTCCTGAGCTGATTAAGCAGTTGGAACAAAAACTGCGCTCGGGTGAGTTGAATCCCCGTCAGCGGGGTTGCGTCACG
CTGTATTGTAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTTTTGGTTATGTATATATTGTTATTTATCCCACTTC
TGCAGCAACACACTAA