Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 868858..869518 | Replicon | chromosome |
Accession | NZ_CP026985 | ||
Organism | Pectobacterium parmentieri strain IFB5619 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A8B3EZX7 |
Locus tag | C5E25_RS04200 | Protein ID | WP_012822581.1 |
Coordinates | 869105..869518 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A0H3I0G9 |
Locus tag | C5E25_RS04195 | Protein ID | WP_012822580.1 |
Coordinates | 868858..869124 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C5E25_RS04175 | 864850..865854 | - | 1005 | WP_103807861.1 | substrate-binding domain-containing protein | - |
C5E25_RS04180 | 865908..866516 | - | 609 | WP_014698756.1 | HD domain-containing protein | - |
C5E25_RS04185 | 866927..867574 | + | 648 | WP_012822578.1 | hemolysin III family protein | - |
C5E25_RS04190 | 867629..868630 | - | 1002 | WP_012822579.1 | tRNA-modifying protein YgfZ | - |
C5E25_RS04195 | 868858..869124 | + | 267 | WP_012822580.1 | FAD assembly factor SdhE | Antitoxin |
C5E25_RS04200 | 869105..869518 | + | 414 | WP_012822581.1 | protein YgfX | Toxin |
C5E25_RS04205 | 869744..870679 | + | 936 | WP_012822582.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
C5E25_RS04210 | 870767..871090 | - | 324 | WP_012822583.1 | hypothetical protein | - |
C5E25_RS04215 | 871119..871637 | - | 519 | WP_012822584.1 | flavodoxin FldB | - |
C5E25_RS04220 | 871965..872981 | + | 1017 | WP_012822585.1 | methionine ABC transporter ATP-binding protein | - |
C5E25_RS04225 | 872974..873642 | + | 669 | WP_012822586.1 | ABC transporter permease | - |
C5E25_RS04230 | 873660..874478 | + | 819 | WP_033071942.1 | MetQ/NlpA family ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16259.20 Da Isoelectric Point: 10.7923
>T96984 WP_012822581.1 NZ_CP026985:869105-869518 [Pectobacterium parmentieri]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
Download Length: 414 bp
>T96984 NZ_CP026985:869105-869518 [Pectobacterium parmentieri]
GTGGCCCAGTGGCAATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGTCTATTAGTGTT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTGTGGCTGTGTTTGGTCACAATGGTGATGTTTGGTTTCA
TCCGTAGCCAAAGGAATATCAAATCGCGGCAAGGGTGCATCACGCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAGTGGCGGATTGTCAAACGACCGTGGTTGCTGAAAAATGGTGTGTTATTGGCATTGCAATCGGCTAATGGGAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGCCAGCTTCTTTTGCAGCAAAAAC
ACTGGGCGAGATGA
GTGGCCCAGTGGCAATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGTCTATTAGTGTT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTGTGGCTGTGTTTGGTCACAATGGTGATGTTTGGTTTCA
TCCGTAGCCAAAGGAATATCAAATCGCGGCAAGGGTGCATCACGCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAGTGGCGGATTGTCAAACGACCGTGGTTGCTGAAAAATGGTGTGTTATTGGCATTGCAATCGGCTAATGGGAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGCCAGCTTCTTTTGCAGCAAAAAC
ACTGGGCGAGATGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10519.99 Da Isoelectric Point: 5.1392
>AT96984 WP_012822580.1 NZ_CP026985:868858-869124 [Pectobacterium parmentieri]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT96984 NZ_CP026985:868858-869124 [Pectobacterium parmentieri]
ATGGAAATCGATAACAAATCACGTATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTGGATATCGCCATCATGCCGTT
TTTTGAGCATGACTATGACACATTAAACGATATAGATAAGCGCACGTTTGTACGCCTGCTACAAAGCGACGATCCCGATT
TATTCAACTGGCTAATGAACCACGGTGAGCCAGAAGACGGAGAGCTAAAACGCATGATTTCCCTTATCCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
ATGGAAATCGATAACAAATCACGTATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTGGATATCGCCATCATGCCGTT
TTTTGAGCATGACTATGACACATTAAACGATATAGATAAGCGCACGTTTGTACGCCTGCTACAAAGCGACGATCCCGATT
TATTCAACTGGCTAATGAACCACGGTGAGCCAGAAGACGGAGAGCTAAAACGCATGATTTCCCTTATCCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3EZX7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3I0G9 |