Detailed information of TA system TA096981

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 552485..553199
• Replicon: chromosome
• Accession: NZ_CP026985
• Organism: Pectobacterium parmentieri strain IFB5619

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: C5E25_RS02720
• Protein ID: WP_103808670.1
• Coordinates: 552879..553199 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E25_RS02715
• Protein ID: WP_103808669.1
• Coordinates: 552485..552820 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E25_RS02690	548205..549137	+	933	WP_121246950.1	hypothetical protein	-
C5E25_RS02695	549232..550119	+	888	WP_103808666.1	50S ribosome-binding GTPase	-
C5E25_RS23125	550303..550461	+	159	WP_155242703.1	hypothetical protein	-
C5E25_RS02700	550608..551441	+	834	WP_103808667.1	hypothetical protein	-
C5E25_RS02705	551499..551849	+	351	WP_005974477.1	hypothetical protein	-
C5E25_RS02710	551972..552445	+	474	WP_103808668.1	DNA repair protein RadC	-
C5E25_RS02715	552485..552820	+	336	WP_103808669.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E25_RS02720	552879..553199	+	321	WP_103808670.1	TA system toxin CbtA family protein	Toxin
C5E25_RS02725	553317..554150	+	834	Protein_533	DUF4942 domain-containing protein	-
C5E25_RS02730	554260..554508	+	249	WP_103808671.1	ribbon-helix-helix domain-containing protein	-
C5E25_RS02735	554512..554787	+	276	WP_039517502.1	type II toxin-antitoxin system RelE/ParE family toxin	-
C5E25_RS02740	554835..555347	+	513	WP_103808672.1	AAA family ATPase	-
C5E25_RS02745	555654..556774	-	1121	Protein_537	IS3 family transposase	-
C5E25_RS02750	556846..558014	+	1169	WP_103808047.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	mgtB / hcp	532080..675143	143063

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12049.71 Da
• Isoelectric Point: 4.5971

>T96981 WP_103808670.1 NZ_CP026985:552879-553199 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAAWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDVLRARRANGLLKA

Nucleotide

• Length: 321 bp

>T96981 NZ_CP026985:552879-553199 [Pectobacterium parmentieri]
ATGCAAACATCACCTGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCCATAGCCGCCTGGCAGCAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACGCCGTTCTGTGAGGAAAACGTGATTCAGGAACATATCG
ATGCTGGCATCACATTGGTCAATGCCGTGAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGACCGCGACGGTTTT
AACTGGCAGGAGCAATCACCGTTTCTTACTGCCGTTGATGTTCTCCGTGCCAGACGTGCTAACGGCTTGCTCAAAGCATA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12529.30 Da
• Isoelectric Point: 5.8292

>AT96981 WP_103808669.1 NZ_CP026985:552485-552820 [Pectobacterium parmentieri]
MSLSDTPEWGLKSAITPRFGARLVQEGNRLHYLADRVSFIGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQGCIT
LYCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Nucleotide

• Length: 336 bp

>AT96981 NZ_CP026985:552485-552820 [Pectobacterium parmentieri]
ATGTCATTATCGGATACCCCGGAATGGGGACTAAAAAGTGCCATCACTCCGCGATTCGGAGCCAGACTGGTGCAGGAGGG
TAACCGTCTGCATTATCTGGCAGACCGGGTCAGCTTTATCGGTACGTTTAGCAAAACAGAAGCCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAACAGAAGCTACGCATGGGGGAACTGAATCCCCGGCAGCAGGGTTGCATCACG
TTGTATTGCAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTTTTGGCTACGTGTATATTGCTATTTATCCCTCTTC
AGCGGCAACACAATAA