Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 371907..372438 Replicon chromosome
Accession NZ_CP026985
Organism Pectobacterium parmentieri strain IFB5619

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag C5E25_RS01785 Protein ID WP_103808553.1
Coordinates 372151..372438 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag C5E25_RS01780 Protein ID WP_103808552.1
Coordinates 371907..372161 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5E25_RS01755 367125..367715 - 591 WP_011091952.1 DnaA initiator-associating protein DiaA -
C5E25_RS01760 367757..368113 - 357 WP_012822117.1 YraN family protein -
C5E25_RS01765 368110..370128 - 2019 WP_014698522.1 penicillin-binding protein activator -
C5E25_RS01770 370190..371077 + 888 WP_014698523.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
C5E25_RS01780 371907..372161 + 255 WP_103808552.1 plasmid stabilization protein Antitoxin
C5E25_RS01785 372151..372438 + 288 WP_103808553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C5E25_RS01790 372620..373408 + 789 WP_033072300.1 4,5-DOPA dioxygenase extradiol -
C5E25_RS01795 373496..374656 - 1161 WP_103808554.1 glutathionylspermidine synthase family protein -
C5E25_RS01800 374668..375336 - 669 WP_012822126.1 DUF1190 family protein -
C5E25_RS01805 375620..377011 - 1392 WP_012822127.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10997.89 Da        Isoelectric Point: 10.7148

>T96979 WP_103808553.1 NZ_CP026985:372151-372438 [Pectobacterium parmentieri]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTQGRSA

Download         Length: 288 bp

>T96979 NZ_CP026985:372151-372438 [Pectobacterium parmentieri]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCAATGAAGGAATGGAAAAAATTAGGGCATCCTGTCAGGGAACAATTCAA
AAAAAAGCTAGTTGAGCGTTTAGAAAATCCTCGAGTCCCTTCGGCTCAACTTCATGGCCGTAAAGACCAGTATAAAATTA
AACTGAAGTCTGCTGGTTACAGGCTGGTGTATTTGGTTCAAGATGAGACCATTACGGTGATGGTCATGGGGGTTGGAAAG
CGCGAAGGTAGCCAGGTTTATTCTGATACTCAAGGTCGCTCTGCTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9284.50 Da        Isoelectric Point: 3.7947

>AT96979 WP_103808552.1 NZ_CP026985:371907-372161 [Pectobacterium parmentieri]
MAFNILTNTVASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT96979 NZ_CP026985:371907-372161 [Pectobacterium parmentieri]
ATGGCTTTCAATATCCTAACTAACACAGTGGCCAGCATTACTGAGCTGAAACGTGACCCAATGGGGACAGTACGGTCCGC
TGAAGGTGAGACTATCGCGATACTGAACCGCAATGAGCCTGCGTTCTATTGTGTGCCTCCTGCCATGTTCGCTTATTTAA
TGGAATTGGCTGAAGATGCAGAACTGGGGCGTACCGTTGATGATCGTATGTCAGAGTTAGCTGACGCGGAAGAGATTTCG
CTCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References