Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3532736..3533461 Replicon chromosome
Accession NZ_CP026983
Organism Pectobacterium parmentieri strain IFB5604

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag C5E23_RS16420 Protein ID WP_103808729.1
Coordinates 3532736..3533056 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag C5E23_RS16425 Protein ID WP_103808730.1
Coordinates 3533126..3533461 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5E23_RS16400 3528579..3529898 + 1320 WP_103808725.1 site-specific integrase -
C5E23_RS16405 3529970..3531019 - 1050 WP_103808726.1 macro domain-containing protein -
C5E23_RS16410 3531033..3531680 - 648 WP_103808727.1 DUF4433 domain-containing protein -
C5E23_RS16415 3531785..3532618 - 834 WP_103808728.1 DUF4942 domain-containing protein -
C5E23_RS16420 3532736..3533056 - 321 WP_103808729.1 TA system toxin CbtA family protein Toxin
C5E23_RS16425 3533126..3533461 - 336 WP_103808730.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
C5E23_RS16430 3533501..3533974 - 474 WP_103808731.1 DNA repair protein RadC -
C5E23_RS16435 3534059..3534292 - 234 WP_040034648.1 membrane protein -
C5E23_RS16440 3534310..3534783 - 474 WP_103808732.1 hypothetical protein -
C5E23_RS16445 3534819..3535388 - 570 WP_121301469.1 hypothetical protein -
C5E23_RS16450 3535570..3536268 - 699 WP_121301470.1 DeoR family transcriptional regulator -
C5E23_RS16455 3536638..3537513 - 876 WP_121301471.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12066.79 Da        Isoelectric Point: 4.5971

>T96978 WP_103808729.1 NZ_CP026983:c3533056-3532736 [Pectobacterium parmentieri]
MQTIPAIPSREDNPCPSPIAAWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T96978 NZ_CP026983:c3533056-3532736 [Pectobacterium parmentieri]
ATGCAAACCATACCTGCAATCCCGTCACGGGAGGATAACCCCTGTCCGTCACCCATAGCCGCCTGGCAGCAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACGCCGTTCTGTGAGGAAAACGTGATTCAGGAACATATCG
ATGCTGGCATCACGTTGGTCAATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGTATCGACCGCGACGGTTTT
AACTGGCAGGAGCAATCACCGTTTCTTACCGCTGTTGATATTCTCCGTGCCAGACGTGCTACCGGCTTGCTCAAAGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12471.28 Da        Isoelectric Point: 6.6869

>AT96978 WP_103808730.1 NZ_CP026983:c3533461-3533126 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAVTPRFGARLVQEGHRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAATQ

Download         Length: 336 bp

>AT96978 NZ_CP026983:c3533461-3533126 [Pectobacterium parmentieri]
ATGCCATCGTCTGATACCCCTGAATGGGGACTAAAATGTGCCGTCACTCCGCGATTCGGAGCCAGATTGGTGCAGGAAGG
TCACCGTCTGCACTATCTGGCAGACCGTGCCAGCATTGTCGGTACGTTTAGCAAAACAGAAGCCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAACAGAAGCTACGCATGGGGGAACTGAATCCCCGTCAGCAGAACTGCGTCACG
CTGCATTGCAACGAATGGATCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGTTATCTATCCCTCTTC
TGCGGCAACACAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References