Detailed information of TA system TA096975

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1453871..1454596
• Replicon: chromosome
• Accession: NZ_CP026983
• Organism: Pectobacterium parmentieri strain IFB5604

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: C5E23_RS06885
• Protein ID: WP_103808442.1
• Coordinates: 1453871..1454191 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E23_RS06890
• Protein ID: WP_103808441.1
• Coordinates: 1454261..1454596 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E23_RS06860	1449074..1449364	-	291	WP_014699065.1	transposase	-
C5E23_RS06865	1449430..1449759	+	330	Protein_1313	IS30 family transposase	-
C5E23_RS06870	1449933..1450562	-	630	WP_103808445.1	hypothetical protein	-
C5E23_RS06875	1450993..1452207	-	1215	WP_103808444.1	tyrosine-type recombinase/integrase	-
C5E23_RS06880	1452920..1453753	-	834	WP_103808443.1	DUF4942 domain-containing protein	-
C5E23_RS06885	1453871..1454191	-	321	WP_103808442.1	TA system toxin CbtA family protein	Toxin
C5E23_RS06890	1454261..1454596	-	336	WP_103808441.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E23_RS06895	1454633..1455106	-	474	WP_121301511.1	DNA repair protein RadC	-
C5E23_RS06900	1455190..1455423	-	234	WP_103808798.1	hypothetical protein	-
C5E23_RS06905	1455441..1455914	-	474	WP_103808799.1	hypothetical protein	-
C5E23_RS06910	1455950..1456519	-	570	Protein_1322	hypothetical protein	-
C5E23_RS06915	1456701..1457399	-	699	WP_121247005.1	DeoR family transcriptional regulator	-
C5E23_RS06920	1457769..1458644	-	876	WP_103808734.1	GTPase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1446805..1472334	25529

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12035.73 Da
• Isoelectric Point: 4.7768

>T96975 WP_103808442.1 NZ_CP026983:c1454191-1453871 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T96975 NZ_CP026983:c1454191-1453871 [Pectobacterium parmentieri]
ATGCAAACATCACCGGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCTATAGCCGTCTGGCAGCAACTACTGAC
TTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACACCATTCTGTGAGGAAAACGTGATTCAGGAGCATATCG
ATGCTGGCATCACGCTGGCCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCGCCGTTTCTTACCGCCGTTGATGTTCTCCGTGCTAGACGTGCAACGGGCTTGCTCAAGGCATA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12643.32 Da
• Isoelectric Point: 5.5351

>AT96975 WP_103808441.1 NZ_CP026983:c1454596-1454261 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAITPRFGARLVQEGHRLHYLEDRASIVGTFSEMEAHHLEEIFPELIKQLEQKLRSGELNPRQRGCVT
LYCNEWTCEADTLGSFGYVYIVIYPTSAATH

Nucleotide

• Length: 336 bp

>AT96975 NZ_CP026983:c1454596-1454261 [Pectobacterium parmentieri]
ATGCCATCATCGGATACCCCGGAGTGGGGATTAAAATGTGCCATCACGCCGCGATTCGGAGCCAGGCTGGTCCAGGAAGG
ACACCGCCTGCATTATCTGGAAGACCGGGCCAGCATTGTCGGTACGTTCAGCGAAATGGAAGCCCACCATCTGGAAGAGA
TCTTTCCTGAGCTGATTAAGCAGTTGGAACAAAAACTGCGCTCGGGTGAGTTGAATCCCCGTCAGCGGGGTTGCGTCACG
CTGTATTGTAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTTTTGGTTATGTATATATTGTTATTTATCCCACTTC
TGCAGCAACACACTAA