Detailed information of TA system TA096971

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 552339..553053
• Replicon: chromosome
• Accession: NZ_CP026983
• Organism: Pectobacterium parmentieri strain IFB5604

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: C5E23_RS02705
• Protein ID: WP_103808670.1
• Coordinates: 552733..553053 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E23_RS02700
• Protein ID: WP_103808669.1
• Coordinates: 552339..552674 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E23_RS02675	548059..548991	+	933	WP_103808665.1	hypothetical protein	-
C5E23_RS02680	549086..549973	+	888	WP_103808666.1	50S ribosome-binding GTPase	-
C5E23_RS22730	550157..550315	+	159	WP_155242703.1	hypothetical protein	-
C5E23_RS02685	550462..551295	+	834	WP_103808667.1	hypothetical protein	-
C5E23_RS02690	551353..551703	+	351	WP_005974477.1	hypothetical protein	-
C5E23_RS02695	551826..552299	+	474	WP_103808668.1	DNA repair protein RadC	-
C5E23_RS02700	552339..552674	+	336	WP_103808669.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E23_RS02705	552733..553053	+	321	WP_103808670.1	TA system toxin CbtA family protein	Toxin
C5E23_RS02710	553171..554004	+	834	Protein_527	DUF4942 domain-containing protein	-
C5E23_RS02715	554114..554362	+	249	WP_103808671.1	ribbon-helix-helix domain-containing protein	-
C5E23_RS02720	554366..554641	+	276	WP_039517502.1	type II toxin-antitoxin system RelE/ParE family toxin	-
C5E23_RS02725	554689..555201	+	513	WP_103808672.1	AAA family ATPase	-
C5E23_RS02730	555508..556628	-	1121	Protein_531	IS3 family transposase	-
C5E23_RS02735	556700..557868	+	1169	WP_103808047.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	mgtB / hcp	531934..674704	142770

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12049.71 Da
• Isoelectric Point: 4.5971

>T96971 WP_103808670.1 NZ_CP026983:552733-553053 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAAWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDVLRARRANGLLKA

Nucleotide

• Length: 321 bp

>T96971 NZ_CP026983:552733-553053 [Pectobacterium parmentieri]
ATGCAAACATCACCTGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCCATAGCCGCCTGGCAGCAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGACACGCCGTTCTGTGAGGAAAACGTGATTCAGGAACATATCG
ATGCTGGCATCACATTGGTCAATGCCGTGAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGACCGCGACGGTTTT
AACTGGCAGGAGCAATCACCGTTTCTTACTGCCGTTGATGTTCTCCGTGCCAGACGTGCTAACGGCTTGCTCAAAGCATA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12529.30 Da
• Isoelectric Point: 5.8292

>AT96971 WP_103808669.1 NZ_CP026983:552339-552674 [Pectobacterium parmentieri]
MSLSDTPEWGLKSAITPRFGARLVQEGNRLHYLADRVSFIGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQGCIT
LYCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Nucleotide

• Length: 336 bp

>AT96971 NZ_CP026983:552339-552674 [Pectobacterium parmentieri]
ATGTCATTATCGGATACCCCGGAATGGGGACTAAAAAGTGCCATCACTCCGCGATTCGGAGCCAGACTGGTGCAGGAGGG
TAACCGTCTGCATTATCTGGCAGACCGGGTCAGCTTTATCGGTACGTTTAGCAAAACAGAAGCCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAACAGAAGCTACGCATGGGGGAACTGAATCCCCGGCAGCAGGGTTGCATCACG
TTGTATTGCAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTTTTGGCTACGTGTATATTGCTATTTATCCCTCTTC
AGCGGCAACACAATAA