Detailed information of TA system TA096965

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeV-yfjZ/CbtA-CbeA
• Location: 4084903..4085624
• Replicon: chromosome
• Accession: NZ_CP026982
• Organism: Pectobacterium parmentieri strain IFB5486

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: C5E22_RS19055
• Protein ID: WP_121326970.1
• Coordinates: 4084903..4085223 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E22_RS19060
• Protein ID: WP_121326973.1
• Coordinates: 4085289..4085624 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E22_RS19035	4081201..4083036	+	1836	WP_005971474.1	RNA polymerase sigma factor RpoD	-
C5E22_RS19040	4083134..4083637	-	504	WP_033070890.1	G/U mismatch-specific DNA glycosylase	-
C5E22_RS19050	4083956..4084789	-	834	WP_121326967.1	DUF4942 domain-containing protein	-
C5E22_RS19055	4084903..4085223	-	321	WP_121326970.1	TA system toxin CbtA family protein	Toxin
C5E22_RS19060	4085289..4085624	-	336	WP_121326973.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E22_RS19065	4085639..4086118	-	480	WP_121326976.1	DNA repair protein RadC	-
C5E22_RS19070	4086130..4086546	-	417	WP_121327030.1	antirestriction protein	-
C5E22_RS19075	4086783..4089917	-	3135	WP_121326979.1	AIDA repeat-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4064389..4086594	22205

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (5-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12046.69 Da
• Isoelectric Point: 5.0359

>T96965 WP_121326970.1 NZ_CP026982:c4085223-4084903 [Pectobacterium parmentieri]
MQISTVPATLSVSSRLSPVQVWQQLLTYLLEQHYGLTLNDTPFHEDAAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQEQTPFLTATDILRAKRATGLMNT

Nucleotide

• Length: 321 bp

>T96965 NZ_CP026982:c4085223-4084903 [Pectobacterium parmentieri]
ATGCAAATCTCAACTGTACCGGCCACGTTGTCGGTTTCGTCACGCCTGTCACCTGTGCAGGTCTGGCAGCAACTTTTAAC
GTATCTACTGGAGCAGCATTACGGCCTGACACTCAACGACACGCCATTCCATGAGGACGCGGCCATTCAGGAACATATCG
AAGCGGGAATAACGCTTGCTGATGCGGTGAATTTCCTTGTGGAACGCTATGAACTGATACGCACTGACCGCAAAGGGTTT
ACATGGCAGGAGCAGACACCGTTCCTGACCGCTACCGATATTCTCAGAGCAAAGCGAGCTACCGGATTAATGAATACGTA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12652.32 Da
• Isoelectric Point: 6.5989

>AT96965 WP_121326973.1 NZ_CP026982:c4085624-4085289 [Pectobacterium parmentieri]
MNKDVTQTWGLKRDITPCFGARLVQEGHRLHFLADRAGFTGSFSEMQARHLDEAFPHFVAHLELMLLSGELNPRYAHSVT
LYRNELTCEADTLGSHGYVYIVIYPSNQVKD

Nucleotide

• Length: 336 bp

>AT96965 NZ_CP026982:c4085624-4085289 [Pectobacterium parmentieri]
ATGAATAAAGACGTTACCCAGACCTGGGGTCTTAAACGAGATATCACACCGTGTTTTGGCGCACGACTGGTGCAGGAAGG
TCATCGTCTGCATTTTCTGGCGGACCGGGCAGGGTTCACCGGTTCATTCAGCGAGATGCAGGCCCGACATCTGGATGAAG
CTTTCCCGCATTTTGTCGCGCATCTGGAGCTGATGTTGCTCTCTGGCGAACTGAATCCCCGCTATGCACACAGCGTAACG
CTTTACCGGAACGAACTGACCTGTGAAGCCGATACGCTGGGCAGTCATGGATATGTGTATATCGTAATTTATCCCTCAAA
TCAGGTTAAAGACTGA