Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 553431..553958 Replicon chromosome
Accession NZ_CP026981
Organism Pectobacterium parmentieri strain IFB5485

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C5E21_RS02715 Protein ID WP_039517502.1
Coordinates 553683..553958 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C5E21_RS02710 Protein ID WP_103808671.1
Coordinates 553431..553679 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5E21_RS22735 549474..549632 + 159 WP_155242703.1 hypothetical protein -
C5E21_RS02680 549779..550612 + 834 WP_103808667.1 hypothetical protein -
C5E21_RS02685 550670..551020 + 351 WP_005974477.1 hypothetical protein -
C5E21_RS02690 551143..551616 + 474 WP_103808668.1 DNA repair protein RadC -
C5E21_RS02695 551656..551991 + 336 WP_103808669.1 type IV toxin-antitoxin system YeeU family antitoxin -
C5E21_RS02700 552050..552370 + 321 WP_103808670.1 TA system toxin CbtA family protein -
C5E21_RS02705 552488..553321 + 834 Protein_527 DUF4942 domain-containing protein -
C5E21_RS02710 553431..553679 + 249 WP_103808671.1 ribbon-helix-helix domain-containing protein Antitoxin
C5E21_RS02715 553683..553958 + 276 WP_039517502.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C5E21_RS02720 554006..554518 + 513 WP_103808672.1 AAA family ATPase -
C5E21_RS02725 554825..555945 - 1121 Protein_531 IS3 family transposase -
C5E21_RS02730 556017..557185 + 1169 WP_103808047.1 IS3 family transposase -
C5E21_RS02735 557160..557471 - 312 WP_103808046.1 hypothetical protein -
C5E21_RS02740 557953..558215 - 263 Protein_534 PAAR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - mgtB / hcp 531251..674021 142770


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11028.25 Da        Isoelectric Point: 5.5034

>T96954 WP_039517502.1 NZ_CP026981:553683-553958 [Pectobacterium parmentieri]
MEIRWTQKAQDDLERIYGFASQYSRHHADEVLDRLIIGTTGIADHPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTIY
IVDLWHTREDR

Download         Length: 276 bp

>T96954 NZ_CP026981:553683-553958 [Pectobacterium parmentieri]
ATGGAAATACGTTGGACGCAAAAGGCACAGGATGACCTTGAACGTATTTATGGGTTTGCCAGCCAGTACAGTCGGCATCA
TGCTGACGAGGTGTTAGATCGCTTGATCATCGGAACCACAGGGATTGCTGACCACCCGAGAATTGGCGTATCTCAGACAA
GATATGAACCACGCGAGGTGAGAAAGATTTTGTTTGATGATTATGAAGTTCACTATGAAATTCAGCACGATACGATTTAT
ATCGTCGATCTTTGGCATACACGAGAAGATCGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9007.39 Da        Isoelectric Point: 8.7560

>AT96954 WP_103808671.1 NZ_CP026981:553431-553679 [Pectobacterium parmentieri]
MGQPAKQTISAQIPAELAAAVESLAIELDRSKSWVIKEALTAMIEERERRHQRVLKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT96954 NZ_CP026981:553431-553679 [Pectobacterium parmentieri]
ATGGGACAACCTGCGAAACAGACGATCAGTGCTCAGATACCCGCCGAACTTGCGGCTGCGGTTGAAAGCCTGGCTATTGA
ATTGGATAGATCCAAAAGCTGGGTGATTAAAGAAGCGCTGACCGCAATGATTGAAGAGAGAGAGCGGCGGCATCAGCGTG
TTTTGAAAGGTCTTGCTGATGTCGATGCGGGAAGAGTAGTAAGCCATGCAGATGTCATCGATTTCGCCAACAAACTGAAA
AAGTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References