Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 3693385..3693911 | Replicon | chromosome |
Accession | NZ_CP026977 | ||
Organism | Pectobacterium parmentieri strain IFB5408 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | A0A8B3FHC0 |
Locus tag | C5E17_RS17360 | Protein ID | WP_033071873.1 |
Coordinates | 3693606..3693911 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | C6C380 |
Locus tag | C5E17_RS17355 | Protein ID | WP_015855076.1 |
Coordinates | 3693385..3693603 (+) | Length | 73 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C5E17_RS17330 | 3689593..3690852 | + | 1260 | WP_069704166.1 | integrase arm-type DNA-binding domain-containing protein | - |
C5E17_RS17335 | 3690958..3691152 | - | 195 | WP_033071869.1 | DUF3950 domain-containing protein | - |
C5E17_RS17340 | 3691338..3691679 | + | 342 | WP_033071870.1 | hypothetical protein | - |
C5E17_RS23720 | 3692271..3692441 | - | 171 | WP_154665134.1 | hypothetical protein | - |
C5E17_RS17350 | 3692583..3693326 | + | 744 | WP_033071872.1 | hypothetical protein | - |
C5E17_RS17355 | 3693385..3693603 | + | 219 | WP_015855076.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
C5E17_RS17360 | 3693606..3693911 | + | 306 | WP_033071873.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
C5E17_RS17365 | 3694017..3694554 | + | 538 | Protein_3326 | exonuclease SbcC | - |
C5E17_RS17370 | 3694652..3695230 | - | 579 | WP_033071875.1 | hypothetical protein | - |
C5E17_RS17375 | 3695232..3696563 | - | 1332 | WP_033071876.1 | hypothetical protein | - |
C5E17_RS17380 | 3697599..3697820 | + | 222 | Protein_3329 | integrase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 3689426..3697376 | 7950 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11773.64 Da Isoelectric Point: 4.4978
>T96936 WP_033071873.1 NZ_CP026977:3693606-3693911 [Pectobacterium parmentieri]
MQFIVYQYRRASRYKMFVDVQSDIVETPKRRMVIPLIEAHNLSEKVNNTLFPLIRIDGEDYRLMTTELSSVPVEVMGEVI
ADLGDYADEIKDAINLMFWGI
MQFIVYQYRRASRYKMFVDVQSDIVETPKRRMVIPLIEAHNLSEKVNNTLFPLIRIDGEDYRLMTTELSSVPVEVMGEVI
ADLGDYADEIKDAINLMFWGI
Download Length: 306 bp
>T96936 NZ_CP026977:3693606-3693911 [Pectobacterium parmentieri]
ATGCAATTCATTGTTTATCAATACAGACGCGCCAGCCGCTACAAAATGTTTGTCGATGTGCAAAGCGATATTGTCGAGAC
ACCCAAGCGGCGCATGGTCATCCCGCTTATCGAAGCACATAACCTGTCTGAGAAAGTGAATAATACGCTGTTTCCTCTGA
TCCGCATCGACGGCGAAGATTATCGGCTGATGACGACTGAACTATCGAGCGTACCTGTTGAAGTCATGGGTGAAGTGATT
GCGGATCTTGGCGACTACGCGGATGAGATCAAAGATGCTATTAATCTTATGTTTTGGGGGATTTGA
ATGCAATTCATTGTTTATCAATACAGACGCGCCAGCCGCTACAAAATGTTTGTCGATGTGCAAAGCGATATTGTCGAGAC
ACCCAAGCGGCGCATGGTCATCCCGCTTATCGAAGCACATAACCTGTCTGAGAAAGTGAATAATACGCTGTTTCCTCTGA
TCCGCATCGACGGCGAAGATTATCGGCTGATGACGACTGAACTATCGAGCGTACCTGTTGAAGTCATGGGTGAAGTGATT
GCGGATCTTGGCGACTACGCGGATGAGATCAAAGATGCTATTAATCTTATGTTTTGGGGGATTTGA
Antitoxin
Download Length: 73 a.a. Molecular weight: 8178.13 Da Isoelectric Point: 7.0135
>AT96936 WP_015855076.1 NZ_CP026977:3693385-3693603 [Pectobacterium parmentieri]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQNGSFADENRNW
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQNGSFADENRNW
Download Length: 219 bp
>AT96936 NZ_CP026977:3693385-3693603 [Pectobacterium parmentieri]
ATGAAACACCGCGTCAGCGTTACCGTGGACAAAGACAATTACCAGGTTCTGAGTGCTGCCGGAGTCAATATTTCCGGGCT
AGTGAATGACGCCATTGGCAAAGAAGCCCGCCGCATCAAGGCTGAGGAGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCGCAGAATGGCTCGTTTGCGGATGAAAACAGGAACTGGTGA
ATGAAACACCGCGTCAGCGTTACCGTGGACAAAGACAATTACCAGGTTCTGAGTGCTGCCGGAGTCAATATTTCCGGGCT
AGTGAATGACGCCATTGGCAAAGAAGCCCGCCGCATCAAGGCTGAGGAGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCGCAGAATGGCTCGTTTGCGGATGAAAACAGGAACTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3FHC0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A250BG46 |