Detailed information of TA system TA096933

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1727630..1728355
• Replicon: chromosome
• Accession: NZ_CP026977
• Organism: Pectobacterium parmentieri strain IFB5408

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: C5E17_RS08170
• Protein ID: WP_121328600.1
• Coordinates: 1728035..1728355 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: C5E17_RS08165
• Protein ID: WP_121328598.1
• Coordinates: 1727630..1727965 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C5E17_RS08130	1722660..1723454	+	795	WP_109411459.1	hypothetical protein	-
C5E17_RS08135	1723580..1724455	+	876	WP_121328590.1	GTPase family protein	-
C5E17_RS08140	1724825..1725523	+	699	WP_121328592.1	DeoR family transcriptional regulator	-
C5E17_RS08145	1725704..1726273	+	570	WP_121328594.1	hypothetical protein	-
C5E17_RS08150	1726309..1726782	+	474	WP_107333350.1	hypothetical protein	-
C5E17_RS08155	1726799..1727038	+	240	WP_116156150.1	hypothetical protein	-
C5E17_RS08160	1727117..1727590	+	474	WP_121328596.1	DNA repair protein RadC	-
C5E17_RS08165	1727630..1727965	+	336	WP_121328598.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
C5E17_RS08170	1728035..1728355	+	321	WP_121328600.1	TA system toxin CbtA family protein	Toxin
C5E17_RS08175	1728473..1729306	+	834	WP_121328602.1	DUF4942 domain-containing protein	-
C5E17_RS08180	1729400..1729630	+	231	WP_121328604.1	antitoxin	-
C5E17_RS08185	1729630..1730058	+	429	WP_121328606.1	tRNA(fMet)-specific endonuclease VapC	-
C5E17_RS08190	1730189..1730386	-	198	WP_162939963.1	transposase	-
C5E17_RS08195	1730449..1730661	-	213	Protein_1558	DUF4102 domain-containing protein	-
C5E17_RS08200	1731416..1731709	+	294	WP_014699387.1	hypothetical protein	-
C5E17_RS08205	1731980..1732162	-	183	WP_014699388.1	hypothetical protein	-
C5E17_RS08210	1732328..1733179	+	852	WP_014699389.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12039.72 Da
• Isoelectric Point: 4.7627

>T96933 WP_121328600.1 NZ_CP026977:1728035-1728355 [Pectobacterium parmentieri]
MQPSPTIPSREDNPCASPIAVWQQLLTYLLEKHYGLTLNDTPFCEDNVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T96933 NZ_CP026977:1728035-1728355 [Pectobacterium parmentieri]
ATGCAACCATCACCTACAATCCCGTCACGGGAGGATAACCCCTGTGCGTCACCTATAGCTGTCTGGCAGCAGCTTCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTCACGCTGAACGATACGCCGTTCTGTGAGGACAATGTGATTCAGGAGCATATCG
ATGCTGGCATCACGTTGGTCAATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGTATCGATCGCAACGGTTTT
AACTGGCAGGAGCAATCGCCATTTCTTACCGCCGTTGATGTTCTCCGCGCCAGACGTGCTACTGGCTTGCTCAAGGCATA
A

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12281.94 Da
• Isoelectric Point: 6.2071

>AT96933 WP_121328598.1 NZ_CP026977:1727630-1727965 [Pectobacterium parmentieri]
VPSSDTPEWGLKCAITPRFGARLVQEGNHLHYLADRASVVGTFSKTEAQSLERCFPELIKQLEQKLRTGELNPRQQGCVT
LHCNEWACEADTLGSVGYVYIVIYPTSAATL

Nucleotide

• Length: 336 bp

>AT96933 NZ_CP026977:1727630-1727965 [Pectobacterium parmentieri]
GTGCCATCATCTGATACCCCGGAATGGGGACTAAAATGTGCCATCACGCCGCGATTCGGGGCCAGGCTGGTTCAGGAAGG
TAACCATCTGCATTATCTGGCAGATCGGGCCAGCGTTGTAGGTACGTTCAGCAAAACAGAAGCCCAAAGTCTGGAACGTT
GCTTCCCTGAGCTGATTAAGCAGTTGGAGCAGAAGCTACGCACGGGTGAACTGAATCCCCGCCAGCAGGGTTGTGTCACG
TTGCATTGCAACGAATGGGCCTGTGAAGCCGATACGCTGGGCAGTGTTGGTTACGTGTATATCGTTATTTATCCAACTTC
TGCTGCAACACTGTAA