Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172129..2172363 Replicon chromosome
Accession NZ_CP026935
Organism Escherichia coli strain CFS3292

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172259..2172362 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172129..2172363 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5F72_RS10390 2168684..2169346 - 663 WP_000944256.1 exodeoxyribonuclease X -
C5F72_RS10395 2169370..2170026 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C5F72_RS10400 2170128..2170358 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C5F72_RS10405 2170497..2170871 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C5F72_RS10410 2170875..2171747 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C5F72_RS10415 2171760..2172101 + 342 WP_000976476.1 YebY family protein -
- 2172129..2172363 - 235 - - Antitoxin
- 2172259..2172362 + 104 - - Toxin
C5F72_RS10420 2172494..2173570 - 1077 WP_001189085.1 phage integrase Arm DNA-binding domain-containing protein -
C5F72_RS10425 2173536..2173817 - 282 WP_001311878.1 excisionase -
C5F72_RS10430 2173924..2174112 - 189 WP_024165285.1 DUF1187 family protein -
- 2173928..2174106 + 179 NuclAT_0 - -
- 2173928..2174106 + 179 NuclAT_0 - -
- 2173928..2174106 + 179 NuclAT_0 - -
- 2173928..2174106 + 179 NuclAT_0 - -
C5F72_RS10435 2174105..2174299 - 195 WP_010989194.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
C5F72_RS10440 2174363..2175415 - 1053 WP_159375964.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2166627..2231780 65153


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96710 NZ_CP026935:2172259-2172362 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT96710 NZ_CP026935:c2172363-2172129 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References