Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1297556..1298184 Replicon chromosome
Accession NZ_CP026923
Organism Pontimonas salivibrio strain CL-TW6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C3B54_RS06525 Protein ID WP_104913779.1
Coordinates 1297556..1297969 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C3B54_RS06530 Protein ID WP_104913780.1
Coordinates 1297960..1298184 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3B54_RS06505 1293410..1294414 - 1005 WP_104913776.1 ABC transporter permease -
C3B54_RS06510 1294417..1295154 - 738 WP_211286285.1 ATP-binding cassette domain-containing protein -
C3B54_RS06515 1295215..1296213 - 999 WP_104913777.1 substrate-binding domain-containing protein -
C3B54_RS06520 1296343..1297344 + 1002 WP_104913778.1 LacI family transcriptional regulator -
C3B54_RS06525 1297556..1297969 - 414 WP_104913779.1 PIN domain nuclease Toxin
C3B54_RS06530 1297960..1298184 - 225 WP_104913780.1 hypothetical protein Antitoxin
C3B54_RS06535 1298642..1299460 - 819 WP_104913781.1 helix-turn-helix domain-containing protein -
C3B54_RS06540 1299457..1300629 - 1173 WP_104913782.1 thiolase family protein -
C3B54_RS06545 1300626..1301276 - 651 WP_104913783.1 3-oxoacid CoA-transferase subunit B -
C3B54_RS06550 1301273..1301950 - 678 WP_104913784.1 3-oxoacid CoA-transferase subunit A -
C3B54_RS06555 1302005..1303132 - 1128 WP_104913785.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(16-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15272.44 Da        Isoelectric Point: 5.6915

>T96621 WP_104913779.1 NZ_CP026923:c1297969-1297556 [Pontimonas salivibrio]
VAIKTWLIDKSAYARLSESPDREVWVERISRGLVRISSITMLEIAYSFQNSSRADEELTNPPLALMPLEYLGARAERRAL
DLQRALLNASEHRGVSIPDLLIAAGAEISGHTLLHVDSDFELIARYSGQRTEKLVLG

Download         Length: 414 bp

>T96621 NZ_CP026923:c1297969-1297556 [Pontimonas salivibrio]
GTGGCGATAAAAACCTGGCTGATTGATAAGTCCGCCTACGCTCGTCTGAGCGAAAGTCCCGACCGTGAGGTCTGGGTTGA
GAGAATATCGCGCGGACTGGTGCGCATCAGCTCCATCACAATGCTCGAAATTGCTTACTCTTTTCAGAATTCCTCGCGCG
CCGATGAGGAGCTGACCAACCCCCCTCTCGCATTGATGCCGCTTGAATACCTGGGCGCCCGAGCAGAACGGCGCGCACTC
GACTTGCAGCGAGCCTTGTTGAACGCCTCCGAGCATCGCGGGGTGAGCATCCCCGATCTCTTGATCGCCGCGGGTGCAGA
AATCTCCGGGCACACCCTGCTACACGTTGACAGCGATTTCGAGCTCATCGCCCGCTACAGCGGTCAGCGGACTGAGAAAT
TGGTGCTGGGCTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8426.58 Da        Isoelectric Point: 4.7730

>AT96621 WP_104913780.1 NZ_CP026923:c1298184-1297960 [Pontimonas salivibrio]
MTDILVRGLSRDVVAKIDDEAARRGVSRNQFLIEFIQRPYVEEDRPKVTVADLERTARAVADLGDPDIMAQAWR

Download         Length: 225 bp

>AT96621 NZ_CP026923:c1298184-1297960 [Pontimonas salivibrio]
ATGACGGACATTCTTGTGCGGGGGCTCAGCCGCGATGTGGTGGCGAAAATCGACGACGAAGCGGCGAGGCGGGGTGTTTC
TCGCAACCAGTTTCTGATCGAGTTCATCCAGCGCCCCTACGTAGAAGAAGACCGACCCAAGGTGACAGTGGCCGATCTGG
AGCGCACTGCCCGTGCGGTCGCGGATCTTGGCGATCCTGACATCATGGCTCAAGCGTGGCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References