Detailed information of TA system TA096620

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazF-vapB/PHD-MazF
• Location: 1200918..1201707
• Replicon: chromosome
• Accession: NZ_CP026923
• Organism: Pontimonas salivibrio strain CL-TW6

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: C3B54_RS06060
• Protein ID: WP_158665566.1
• Coordinates: 1201348..1201707 (-)
• Length: 120 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: C3B54_RS06055
• Protein ID: WP_104913697.1
• Coordinates: 1200918..1201202 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3B54_RS06020	1196294..1197598	-	1305	WP_158665563.1	hypothetical protein	-
C3B54_RS06025	1197780..1198808	+	1029	WP_158665564.1	NADP-dependent oxidoreductase	-
C3B54_RS06030	1198979..1199257	+	279	WP_104913692.1	hypothetical protein	-
C3B54_RS06035	1199254..1199658	+	405	WP_158665565.1	type II toxin-antitoxin system VapC family toxin	-
C3B54_RS06040	1199756..1199995	+	240	WP_104913694.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
C3B54_RS06045	1200124..1200528	-	405	WP_104913695.1	type II toxin-antitoxin system VapC family toxin	-
C3B54_RS06050	1200525..1200809	-	285	WP_104913696.1	hypothetical protein	-
C3B54_RS06055	1200918..1201202	-	285	WP_104913697.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
C3B54_RS06060	1201348..1201707	-	360	WP_158665566.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
C3B54_RS08785	1201701..1201943	-	243	WP_158665567.1	ribbon-helix-helix domain-containing protein	-
C3B54_RS06070	1202152..1203366	+	1215	WP_104913700.1	hypothetical protein	-
C3B54_RS06075	1203406..1204419	+	1014	WP_104914304.1	ATP-binding cassette domain-containing protein	-
C3B54_RS06080	1204454..1205254	+	801	WP_104914303.1	ABC transporter permease subunit	-
C3B54_RS06085	1205354..1205944	-	591	WP_104913701.1	hypothetical protein	-
C3B54_RS06090	1206413..1206655	+	243	WP_104913702.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (5-114)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 120 a.a.
• Molecular weight: 12916.71 Da
• Isoelectric Point: 8.1352

>T96620 WP_158665566.1 NZ_CP026923:c1201707-1201348 [Pontimonas salivibrio]
VVGPQRGHIAWVDLGEPTGSEASTRRPCVVISNNSANRVAPSLGRGVINVIPLTTNLQRAVHSHLVLTATQSGLPRDSAV
QVEQIRAVDISRLQPTSNRVPTGLLEHIEWEVRVHLDLL

Nucleotide

• Length: 360 bp

>T96620 NZ_CP026923:c1201707-1201348 [Pontimonas salivibrio]
GTGGTAGGTCCACAACGCGGTCACATTGCCTGGGTTGATCTAGGCGAACCCACAGGCTCTGAAGCCAGCACCAGGAGGCC
TTGTGTGGTCATCTCGAACAATTCAGCAAATCGTGTCGCGCCGTCGCTCGGCCGTGGGGTCATCAACGTGATTCCGCTGA
CGACTAACCTGCAGCGAGCCGTCCATTCTCACTTGGTACTCACGGCCACACAGTCAGGGCTACCGCGCGATAGCGCCGTC
CAAGTCGAACAAATCCGCGCGGTGGACATTTCACGGCTCCAGCCCACCTCGAATCGAGTGCCCACAGGGTTACTGGAGCA
CATCGAATGGGAAGTCCGGGTTCACCTGGACCTTCTGTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10494.95 Da
• Isoelectric Point: 4.7360

>AT96620 WP_104913697.1 NZ_CP026923:c1201202-1200918 [Pontimonas salivibrio]
VDNTHVGLRQLGQNVSRVMERVKRGEILVVTEFGKPIAKISPVREPQTLEEAVEMGQITPASADLAEFLAREPLPSGDGE
LLSETLERMRRDER

Nucleotide

• Length: 285 bp

>AT96620 NZ_CP026923:c1201202-1200918 [Pontimonas salivibrio]
GTGGATAACACTCACGTTGGGCTGCGTCAACTAGGTCAAAATGTCTCCCGCGTCATGGAACGAGTCAAACGGGGGGAAAT
CCTGGTGGTCACTGAATTTGGTAAACCGATTGCAAAGATCTCTCCGGTGCGTGAGCCCCAAACCCTTGAAGAAGCCGTCG
AAATGGGTCAGATCACACCCGCGTCGGCCGATTTAGCAGAATTTCTCGCCCGGGAGCCCCTTCCCTCGGGCGATGGGGAA
TTGCTGTCGGAGACTCTGGAGCGAATGCGACGCGACGAAAGATGA