Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1487404..1487637 Replicon chromosome
Accession NZ_CP026878
Organism Shigella dysenteriae strain 07-3308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1487404..1487507 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1487404..1487637 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P62_RS08210 1483168..1483287 - 120 WP_001131442.1 hypothetical protein -
C1P62_RS08215 1483248..1483433 - 186 WP_023637031.1 hypothetical protein -
C1P62_RS08230 1484471..1484752 + 282 WP_078164586.1 excisionase -
C1P62_RS08235 1484867..1485564 - 698 Protein_1570 IS1 family transposase -
C1P62_RS08240 1485641..1486797 + 1157 WP_134801760.1 IS3-like element IS600 family transposase -
C1P62_RS08245 1486843..1487282 + 440 Protein_1572 tyrosine-type recombinase/integrase -
- 1487404..1487507 - 104 - - Toxin
- 1487404..1487637 + 234 - - Antitoxin
C1P62_RS08250 1487665..1488006 - 342 WP_000976472.1 YebY family protein -
C1P62_RS08255 1488019..1488891 - 873 WP_000879288.1 copper homeostasis membrane protein CopD -
C1P62_RS08260 1488895..1489269 - 375 WP_000168738.1 CopC domain-containing protein YobA -
C1P62_RS08265 1489408..1489638 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C1P62_RS08270 1489740..1490396 + 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
C1P62_RS08275 1490420..1491082 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96513 NZ_CP026878:c1487507-1487404 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT96513 NZ_CP026878:1487404-1487637 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References