Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4614327..4614560 | Replicon | chromosome |
| Accession | NZ_CP026840 | ||
| Organism | Shigella dysenteriae strain ATCC 9753 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4614328..4614430 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4614327..4614560 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P67_RS24230 | 4609944..4610240 | + | 297 | WP_001277359.1 | host-nuclease inhibitor Gam family protein | - |
| C1P67_RS24235 | 4610365..4610714 | + | 350 | Protein_4674 | transposase | - |
| C1P67_RS24245 | 4611963..4612404 | + | 442 | Protein_4676 | phage integrase SAM-like domain-containing protein | - |
| C1P67_RS24255 | 4613669..4614196 | + | 528 | Protein_4678 | tyrosine-type recombinase/integrase | - |
| - | 4614327..4614560 | + | 234 | - | - | Antitoxin |
| - | 4614328..4614430 | - | 103 | - | - | Toxin |
| C1P67_RS24260 | 4614588..4614929 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P67_RS24265 | 4614942..4615814 | - | 873 | WP_000879300.1 | copper homeostasis membrane protein CopD | - |
| C1P67_RS24270 | 4615818..4616192 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P67_RS24275 | 4616331..4616561 | + | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C1P67_RS24280 | 4616663..4617319 | + | 657 | WP_000011670.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P67_RS24285 | 4617343..4618005 | + | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | ipaH9.8 | 4596279..4614929 | 18650 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T96414 NZ_CP026840:c4614430-4614328 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCAAGAGCCATTTCTCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCAAGAGCCATTTCTCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 234 bp
>AT96414 NZ_CP026840:4614327-4614560 [Shigella dysenteriae]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAAGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAAGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
