Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1354299..1354533 Replicon chromosome
Accession NZ_CP026836
Organism Shigella boydii strain ATCC 49812

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1354300..1354403 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1354299..1354533 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P56_RS07130 1349858..1350154 + 297 WP_001277359.1 host-nuclease inhibitor Gam family protein -
C1P56_RS07135 1350160..1350972 + 813 WP_241560024.1 AAA family ATPase -
C1P56_RS07140 1351013..1352155 - 1143 WP_134796357.1 IS3 family transposase -
C1P56_RS07145 1352271..1352510 + 240 WP_000932577.1 hypothetical protein -
C1P56_RS07150 1352550..1352738 + 189 WP_000276806.1 DUF1187 family protein -
- 1352556..1352734 - 179 NuclAT_1 - -
- 1352556..1352734 - 179 NuclAT_1 - -
- 1352556..1352734 - 179 NuclAT_1 - -
- 1352556..1352734 - 179 NuclAT_1 - -
C1P56_RS07155 1352845..1353126 + 282 WP_077901267.1 excisionase -
C1P56_RS07160 1353092..1354168 + 1077 WP_001189098.1 phage integrase Arm DNA-binding domain-containing protein -
- 1354299..1354533 + 235 - - Antitoxin
- 1354300..1354403 - 104 - - Toxin
C1P56_RS07165 1354561..1354902 - 342 WP_000976480.1 YebY family protein -
C1P56_RS07170 1354915..1355787 - 873 WP_000879307.1 copper homeostasis membrane protein CopD -
C1P56_RS07175 1355791..1356165 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C1P56_RS07180 1356304..1356534 + 231 WP_000916767.1 DNA polymerase III subunit theta -
C1P56_RS07185 1356636..1357291 + 656 Protein_1409 carbon-nitrogen hydrolase family protein YobB -
C1P56_RS07190 1357315..1357977 + 663 WP_000944257.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1351013..1352155 1142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96368 NZ_CP026836:c1354403-1354300 [Shigella boydii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT96368 NZ_CP026836:1354299-1354533 [Shigella boydii]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References