Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 681916..682150 | Replicon | chromosome |
| Accession | NZ_CP026834 | ||
| Organism | Shigella dysenteriae strain ATCC 49347 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 681917..682020 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 681916..682150 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C5B83_RS03720 | 677124..677471 | - | 348 | WP_046891812.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| C5B83_RS03725 | 677468..677848 | - | 381 | WP_001333468.1 | transposase | - |
| C5B83_RS03730 | 677954..678303 | + | 350 | Protein_728 | transposase | - |
| C5B83_RS03740 | 679552..679993 | + | 442 | Protein_730 | integrase | - |
| C5B83_RS03750 | 681258..681785 | + | 528 | Protein_732 | tyrosine-type recombinase/integrase | - |
| - | 681916..682150 | + | 235 | - | - | Antitoxin |
| - | 681917..682020 | - | 104 | - | - | Toxin |
| C5B83_RS03755 | 682178..682519 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C5B83_RS03760 | 682532..683353 | - | 822 | WP_046891729.1 | copper homeostasis membrane protein CopD | - |
| C5B83_RS03765 | 683459..684687 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| C5B83_RS03770 | 684744..685118 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C5B83_RS03775 | 685257..685487 | + | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C5B83_RS03780 | 685589..686245 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C5B83_RS03785 | 686269..686931 | + | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | ipaH9.8 | 663127..682519 | 19392 | |
| - | inside | IScluster/Tn | - | - | 668146..684687 | 16541 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96336 NZ_CP026834:c682020-681917 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96336 NZ_CP026834:681916-682150 [Shigella dysenteriae]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
