Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2563661..2563895 | Replicon | chromosome |
| Accession | NZ_CP026832 | ||
| Organism | Shigella dysenteriae strain ATCC 49346 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2563662..2563765 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2563661..2563895 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C5B81_RS13510 | 2558869..2559216 | - | 348 | WP_000612626.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| C5B81_RS13515 | 2559213..2559593 | - | 381 | WP_001333468.1 | transposase | - |
| C5B81_RS13520 | 2559699..2560048 | + | 350 | Protein_2600 | transposase | - |
| C5B81_RS13530 | 2561297..2561738 | + | 442 | Protein_2602 | integrase | - |
| C5B81_RS13540 | 2563003..2563530 | + | 528 | Protein_2604 | tyrosine-type recombinase/integrase | - |
| - | 2563661..2563895 | + | 235 | - | - | Antitoxin |
| - | 2563662..2563765 | - | 104 | - | - | Toxin |
| C5B81_RS13545 | 2563923..2564264 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C5B81_RS13550 | 2564277..2565098 | - | 822 | WP_046891729.1 | copper homeostasis membrane protein CopD | - |
| C5B81_RS13555 | 2565204..2566432 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| C5B81_RS13560 | 2566489..2566863 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C5B81_RS13565 | 2567002..2567232 | + | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C5B81_RS13570 | 2567334..2567990 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C5B81_RS13575 | 2568014..2568676 | + | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 2526573..2578988 | 52415 | |
| - | inside | IScluster/Tn | - | - | 2547417..2566432 | 19015 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96312 NZ_CP026832:c2563765-2563662 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96312 NZ_CP026832:2563661-2563895 [Shigella dysenteriae]
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
