Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2869861..2870095 Replicon chromosome
Accession NZ_CP026828
Organism Shigella dysenteriae strain ATCC 12037

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2869991..2870094 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2869861..2870095 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P70_RS14890 2865462..2865692 - 231 WP_000916761.1 DNA polymerase III subunit theta -
C1P70_RS14895 2865831..2866205 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C1P70_RS14900 2866209..2866565 + 357 Protein_2860 hypothetical protein -
C1P70_RS14905 2866623..2867320 + 698 WP_230201452.1 IS1-like element IS1A family transposase -
C1P70_RS14910 2867336..2868190 + 855 Protein_2862 fimbrial usher FimD -
C1P70_RS14920 2868952..2869479 + 528 Protein_2864 CopD family protein -
C1P70_RS14925 2869492..2869833 + 342 WP_000976476.1 YebY family protein -
- 2869861..2870095 - 235 - - Antitoxin
- 2869991..2870094 + 104 - - Toxin
C1P70_RS14930 2870226..2870753 - 528 Protein_2866 tyrosine-type recombinase/integrase -
C1P70_RS14935 2870819..2871975 + 1157 WP_129592867.1 IS3-like element IS600 family transposase -
C1P70_RS26760 2872018..2872450 - 433 Protein_2868 integrase -
C1P70_RS14950 2873308..2874476 + 1169 WP_094096507.1 IS3-like element IS911 family transposase -
C1P70_RS14955 2874485..2874834 - 350 Protein_2871 transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - fimD / ipaH9.8 2866817..2891089 24272


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96270 NZ_CP026828:2869991-2870094 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT96270 NZ_CP026828:c2870095-2869861 [Shigella dysenteriae]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References