Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1681801..1682035 | Replicon | chromosome |
| Accession | NZ_CP026819 | ||
| Organism | Shigella dysenteriae strain 96-265 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1681802..1681905 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1681801..1682035 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P77_RS09705 | 1677009..1677356 | - | 348 | WP_000612626.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| C1P77_RS09710 | 1677353..1677733 | - | 381 | WP_001333468.1 | transposase | - |
| C1P77_RS09715 | 1677839..1678188 | + | 350 | Protein_1779 | transposase | - |
| C1P77_RS09725 | 1679437..1679878 | + | 442 | Protein_1781 | integrase | - |
| C1P77_RS09735 | 1681143..1681670 | + | 528 | Protein_1783 | tyrosine-type recombinase/integrase | - |
| - | 1681801..1682035 | + | 235 | - | - | Antitoxin |
| - | 1681802..1681905 | - | 104 | - | - | Toxin |
| C1P77_RS09740 | 1682063..1682404 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P77_RS09745 | 1682417..1683238 | - | 822 | WP_046891729.1 | copper homeostasis membrane protein CopD | - |
| C1P77_RS09750 | 1683344..1684572 | + | 1229 | WP_167544908.1 | IS3-like element IS2 family transposase | - |
| C1P77_RS09755 | 1684629..1685003 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P77_RS09760 | 1685142..1685372 | + | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C1P77_RS09765 | 1685474..1686130 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P77_RS09770 | 1686154..1686816 | + | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1663124..1682404 | 19280 | |
| - | inside | IScluster/Tn | - | ipaH9.8 | 1659170..1684572 | 25402 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96208 NZ_CP026819:c1681905-1681802 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96208 NZ_CP026819:1681801-1682035 [Shigella dysenteriae]
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
