Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1971772..1972006 | Replicon | chromosome |
| Accession | NZ_CP026815 | ||
| Organism | Shigella dysenteriae strain 93-119 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1971902..1972005 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1971772..1972006 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P76_RS10315 | 1966992..1967654 | - | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
| C1P76_RS10320 | 1967678..1968334 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P76_RS10325 | 1968436..1968666 | - | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C1P76_RS10330 | 1968805..1969179 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P76_RS10340 | 1970570..1971390 | + | 821 | Protein_2000 | copper homeostasis membrane protein CopD | - |
| C1P76_RS10345 | 1971403..1971744 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1971772..1972006 | - | 235 | - | - | Antitoxin |
| - | 1971902..1972005 | + | 104 | - | - | Toxin |
| C1P76_RS10350 | 1972137..1972664 | - | 528 | Protein_2002 | tyrosine-type recombinase/integrase | - |
| C1P76_RS10355 | 1972730..1973886 | + | 1157 | WP_094096479.1 | IS3-like element IS600 family transposase | - |
| C1P76_RS10360 | 1973929..1974370 | - | 442 | Protein_2004 | integrase | - |
| C1P76_RS10365 | 1974442..1975610 | + | 1169 | WP_094112582.1 | IS3-like element IS911 family transposase | - |
| C1P76_RS10370 | 1975619..1975968 | - | 350 | Protein_2006 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1962245..2024516 | 62271 | |
| - | inside | IScluster/Tn | - | ipaH9.8 | 1969236..1997674 | 28438 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96185 NZ_CP026815:1971902-1972005 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96185 NZ_CP026815:c1972006-1971772 [Shigella dysenteriae]
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
