Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1180199..1180432 Replicon chromosome
Accession NZ_CP026811
Organism Shigella flexneri strain 64-5500

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1180200..1180303 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1180199..1180432 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P83_RS06315 1175350..1176006 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
C1P83_RS06325 1176520..1177341 - 822 Protein_1227 IS3-like element IS600 family transposase -
C1P83_RS06340 1179551..1180078 + 528 Protein_1230 tyrosine-type recombinase/integrase -
- 1180199..1180432 + 234 - - Antitoxin
- 1180200..1180303 - 104 - - Toxin
C1P83_RS06345 1180460..1180801 - 342 WP_000976476.1 YebY family protein -
C1P83_RS06350 1180814..1181635 - 822 WP_000959864.1 copper homeostasis membrane protein CopD -
C1P83_RS06355 1181690..1182064 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C1P83_RS06360 1182203..1182433 + 231 WP_000916761.1 DNA polymerase III subunit theta -
C1P83_RS06365 1182535..1183191 + 657 WP_000011642.1 carbon-nitrogen hydrolase family protein YobB -
C1P83_RS06370 1183215..1183877 + 663 WP_000944260.1 exodeoxyribonuclease X -
C1P83_RS06375 1183874..1185016 - 1143 Protein_1237 prolyl oligopeptidase family serine peptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96133 NZ_CP026811:c1180303-1180200 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT96133 NZ_CP026811:1180199-1180432 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References