Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 922836..923070 Replicon chromosome
Accession NZ_CP026807
Organism Shigella dysenteriae strain 204/96

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 922966..923069 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 922836..923070 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P75_RS04930 918055..918717 - 663 WP_000944260.1 exodeoxyribonuclease X -
C1P75_RS04935 918741..919397 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
C1P75_RS04940 919499..919729 - 231 WP_000916761.1 DNA polymerase III subunit theta -
C1P75_RS04945 919868..920242 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C1P75_RS04955 921633..922454 + 822 WP_046891729.1 copper homeostasis membrane protein CopD -
C1P75_RS04960 922467..922808 + 342 WP_000976476.1 YebY family protein -
- 922836..923070 - 235 - - Antitoxin
- 922966..923069 + 104 - - Toxin
C1P75_RS04965 923201..923728 - 528 Protein_955 tyrosine-type recombinase/integrase -
C1P75_RS04970 923794..924950 + 1157 WP_094096479.1 IS3-like element IS600 family transposase -
C1P75_RS04975 924993..925434 - 442 Protein_957 integrase -
C1P75_RS04980 925506..926674 + 1169 WP_094112582.1 IS3-like element IS911 family transposase -
C1P75_RS04985 926683..927032 - 350 Protein_959 transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - ipaH9.8 920299..948740 28441


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96106 NZ_CP026807:922966-923069 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATTGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT96106 NZ_CP026807:c923070-922836 [Shigella dysenteriae]
TAAAAAAAGACCGAATACAATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References