Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 801335..801569 | Replicon | chromosome |
| Accession | NZ_CP026805 | ||
| Organism | Shigella dysenteriae strain 2017C-4522 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 801336..801439 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 801335..801569 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P73_RS04450 | 796543..796890 | - | 348 | WP_046891812.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| C1P73_RS04455 | 796887..797267 | - | 381 | WP_001333468.1 | transposase | - |
| C1P73_RS04460 | 797373..797722 | + | 350 | Protein_870 | transposase | - |
| C1P73_RS04470 | 798971..799412 | + | 442 | Protein_872 | integrase | - |
| C1P73_RS04480 | 800677..801204 | + | 528 | Protein_874 | tyrosine-type recombinase/integrase | - |
| - | 801335..801569 | + | 235 | - | - | Antitoxin |
| - | 801336..801439 | - | 104 | - | - | Toxin |
| C1P73_RS04485 | 801597..801938 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P73_RS04490 | 801951..802772 | - | 822 | WP_046891729.1 | copper homeostasis membrane protein CopD | - |
| C1P73_RS04495 | 802878..804106 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| C1P73_RS04500 | 804163..804537 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P73_RS04505 | 804676..804906 | + | 231 | WP_000916761.1 | DNA polymerase III subunit theta | - |
| C1P73_RS04510 | 805008..805664 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P73_RS04515 | 805688..806350 | + | 663 | WP_000944260.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 787565..804106 | 16541 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96079 NZ_CP026805:c801439-801336 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCTCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96079 NZ_CP026805:801335-801569 [Shigella dysenteriae]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGAGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
